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Bioactive fraction of Musa balbisiana seed mitigates D-galactose-induced brain aging via SIRT1/PGC-1α/FoxO3a activation and intestinal barrier dysfunction by modulating gut microbiota and core metabolites.

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Title: Bioactive fraction of Musa balbisiana seed mitigates D-galactose-induced brain aging via SIRT1/PGC-1α/FoxO3a activation and intestinal barrier dysfunction by modulating gut microbiota and core metabolites.
Authors: Gurumayum N; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India; Department of Zoology, Gauhati University, Guwahati, 781014, India., Devi MB; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India; Department of Biotechnology, Gauhati University, Guwahati, 781014, India., Khound P; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India; Department of Zoology, Gauhati University, Guwahati, 781014, India., Bhattacharya A; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India., Sarma H; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India., Khan MR; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India. Electronic address: mojibur.khan@iasst.gov.in., Devi R; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India; Department of Zoology, Gauhati University, Guwahati, 781014, India. Electronic address: rajiasst@gmail.com.
Source: Free radical biology & medicine [Free Radic Biol Med] 2025 Jan; Vol. 226, pp. 43-55. Date of Electronic Publication: 2024 Nov 12.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Bioactive fraction of Musa balbisiana seed mitigates D-galactose-induced brain aging via SIRT1/PGC-1α/FoxO3a activation and intestinal barrier dysfunction by modulating gut microbiota and core metabolites.
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  Data: <searchLink fieldCode="AU" term="%22Gurumayum+N%22">Gurumayum N</searchLink>; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India; Department of Zoology, Gauhati University, Guwahati, 781014, India.<br /><searchLink fieldCode="AU" term="%22Devi+MB%22">Devi MB</searchLink>; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India; Department of Biotechnology, Gauhati University, Guwahati, 781014, India.<br /><searchLink fieldCode="AU" term="%22Khound+P%22">Khound P</searchLink>; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India; Department of Zoology, Gauhati University, Guwahati, 781014, India.<br /><searchLink fieldCode="AU" term="%22Bhattacharya+A%22">Bhattacharya A</searchLink>; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India.<br /><searchLink fieldCode="AU" term="%22Sarma+H%22">Sarma H</searchLink>; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India.<br /><searchLink fieldCode="AU" term="%22Khan+MR%22">Khan MR</searchLink>; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India. Electronic address: mojibur.khan@iasst.gov.in.<br /><searchLink fieldCode="AU" term="%22Devi+R%22">Devi R</searchLink>; Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati-781035, Assam, India; Department of Zoology, Gauhati University, Guwahati, 781014, India. Electronic address: rajiasst@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%228709159%22">Free radical biology & medicine</searchLink> [Free Radic Biol Med] 2025 Jan; Vol. 226, pp. 43-55. <i>Date of Electronic Publication: </i>2024 Nov 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8709159 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4596 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208915849%22">08915849 </searchLink><i>NLM ISO Abbreviation: </i>Free Radic Biol Med <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.freeradbiomed.2024.11.016
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