Cryo-EM characterization of the anydromuropeptide permease AmpG central to bacterial fitness and β-lactam antibiotic resistance.
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| Title: | Cryo-EM characterization of the anydromuropeptide permease AmpG central to bacterial fitness and β-lactam antibiotic resistance. |
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| Authors: | Sverak HE; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, Canada.; Centre for Blood Research, University of British Columbia, Vancouver, Canada., Yaeger LN; Department of Biochemistry and Biomedical Sciences and the Michael G. DeGroote Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Worrall LJ; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, Canada.; Centre for Blood Research, University of British Columbia, Vancouver, Canada.; High Resolution Macromolecular Cryo-Electron Microscopy (HRMEM) Facility, University of British Columbia, Vancouver, Canada., Vacariu CM; Department of Chemistry, University of British Columbia, Vancouver, Canada., Glenwright AJ; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, Canada.; Centre for Blood Research, University of British Columbia, Vancouver, Canada., Vuckovic M; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, Canada.; Centre for Blood Research, University of British Columbia, Vancouver, Canada., Al Azawi ZD; Department of Biochemistry and Biomedical Sciences and the Michael G. DeGroote Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Lamers RP; Department of Biochemistry and Biomedical Sciences and the Michael G. DeGroote Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Marko VA; Department of Biochemistry and Biomedical Sciences and the Michael G. DeGroote Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Skorupski C; Department of Biochemistry and Biomedical Sciences and the Michael G. DeGroote Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Soni AS; Department of Chemistry, University of British Columbia, Vancouver, Canada., Tanner ME; Department of Chemistry, University of British Columbia, Vancouver, Canada., Burrows LL; Department of Biochemistry and Biomedical Sciences and the Michael G. DeGroote Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Strynadka NC; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, Canada. ncjs@mail.ubc.ca.; Centre for Blood Research, University of British Columbia, Vancouver, Canada. ncjs@mail.ubc.ca.; High Resolution Macromolecular Cryo-Electron Microscopy (HRMEM) Facility, University of British Columbia, Vancouver, Canada. ncjs@mail.ubc.ca. |
| Source: | Nature communications [Nat Commun] 2024 Nov 16; Vol. 15 (1), pp. 9936. Date of Electronic Publication: 2024 Nov 16. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-024-54219-9 |
