Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer's disease.

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Title: Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer's disease.
Authors: Hofmann A; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Häsler LM; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Lambert M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Kaeser SA; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Gräber-Sultan S; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., Obermüller U; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Kuder-Buletta E; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., la Fougere C; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Nuclear Medicine and Clinical Molecular Imaging, University Hospital Tübingen, Tübingen, Germany., Laske C; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany., Vöglein J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Department of Neurology, Ludwig Maximilians-Universität München, Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany., Levin J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Department of Neurology, Ludwig Maximilians-Universität München, Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany., Fox NC; Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK., Ryan NS; Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK., Zetterberg H; Department Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden., Llibre-Guerra JJ; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Perrin RJ; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Ibanez L; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA., Schofield PR; Neuroscience Research Australia, Randwick, NSW, Australia.; School of Biomedical Sciences, Faculty of Medicine and Health, University of New South Wales, Sydney, Australia., Brooks WS; Neuroscience Research Australia, Randwick, NSW, Australia.; School of Clinical Medicine, Faculty of Medicine and Health Sydney, University of New South Wales, Sydney, Australia., Day GS; Department of Neurology, Mayo Clinic in Florida, Jacksonville, FL, USA., Farlow MR; Indiana Alzheimer Disease Center and Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Allegri RF; Instituto Neurológico FLENI, Buenos Aires, Argentina., Chrem Mendez P; Instituto Neurológico FLENI, Buenos Aires, Argentina., Ikeuchi T; Brain Research Institute, Niigata University, Niigata, Japan., Kasuga K; Brain Research Institute, Niigata University, Niigata, Japan., Lee JH; Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea., Roh JH; Departments of Neurology and Physiology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, South Korea., Mori H; Faculty of Medicine, Osaka Metropolitan University, Nagaoka Sutoku University, Osaka, Japan., Lopera F; Grupo de Neurociencias de Antioquia (GNA), Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia., Bateman RJ; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., McDade E; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Gordon BA; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Chhatwal JP; Department of Neurology, Harvard Medical School, Boston, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Brigham and Women's Hospital Boston, Boston, MA, USA., Jucker M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany. mathias.jucker@uni-tuebingen.de.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany. mathias.jucker@uni-tuebingen.de., Schultz SA; Department of Neurology, Harvard Medical School, Boston, MA, USA. saschultz@mgh.harvard.edu.; Massachusetts General Hospital, Boston, MA, USA. saschultz@mgh.harvard.edu.
Corporate Authors: Dominantly Inherited Alzheimer Network
Source: Nature communications [Nat Commun] 2024 Nov 18; Vol. 15 (1), pp. 9982. Date of Electronic Publication: 2024 Nov 18.
Publication Type: Comparative Study; Journal Article; Multicenter Study; Observational Study; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-024-52937-8