Diffuse pediatric high-grade glioma of methylation-based RTK2A and RTK2B subclasses present distinct radiological and histomolecular features including Gliomatosis cerebri phenotype.
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| Title: | Diffuse pediatric high-grade glioma of methylation-based RTK2A and RTK2B subclasses present distinct radiological and histomolecular features including Gliomatosis cerebri phenotype. |
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| Authors: | Tauziède-Espariat A; Department of Neuropathology, GHU Paris-Psychiatrie et Neurosciences, Sainte-Anne Hospital, 1, Rue Cabanis, 75014, Paris, France. a.tauziede-espariat@ghu-paris.fr.; Inserm, UMR 1266, IMA-Brain, Institut de Psychiatrie et Neurosciences de Paris, Paris, France. a.tauziede-espariat@ghu-paris.fr., Friker LL; Institute of Neuropathology, DGNN Brain Tumor Reference Center, University of Bonn Medical Center, Bonn, Germany., Nussbaumer G; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria., Bison B; Diagnostic and Interventional Neuroradiology, Faculty of Medicine, University of Augsburg, Augsburg, Germany.; Neuroradiological Reference Center for the Pediatric Brain Tumor (HIT) Studies of the German Society of Pediatric Oncology and Hematology, Faculty of Medicine, University Augsburg, Augsburg, Germany., Dangouloff-Ros V; Pediatric Radiology Department, Hôpital Necker Enfants Malades, AP-HP, Paris, France.; Université Paris Cité, UMR 1163, Institut Imagine and INSERM U1299, Paris, France., Métais A; Department of Neuropathology, GHU Paris-Psychiatrie et Neurosciences, Sainte-Anne Hospital, 1, Rue Cabanis, 75014, Paris, France.; Inserm, UMR 1266, IMA-Brain, Institut de Psychiatrie et Neurosciences de Paris, Paris, France., Sumerauer D; Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic., Zamecnik J; Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic., Benesch M; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria., Perwein T; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria., van Vuurden D; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Wesseling P; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Pathology, Amsterdam UMC, Amsterdam, The Netherlands., La Madrid AM; Pediatric Neuro-Oncology, Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu, Barcelona, Spain., Garrè ML; Neuro-Oncology Unit, IRCSS Istituto Giannina Gaslini, Genoa, Italy., Antonelli M; Department of Radiological, Oncological and Anatomo-Pathological Sciences, Sapienza University, Rome, Italy., Giangaspero F; Department of Radiological, Oncological and Anatomo-Pathological Sciences, Sapienza University, Rome, Italy., Pietsch T; Institute of Neuropathology, DGNN Brain Tumor Reference Center, University of Bonn Medical Center, Bonn, Germany., Sturm D; Division of Pediatric Glioma Research, Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany., Jones DTW; Division of Pediatric Glioma Research, Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Pfister SM; Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany.; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Heidelberg, Germany., Grabovska Y; Division of Molecular Pathology, Institute of Cancer Research, London, UK., Mackay A; Division of Molecular Pathology, Institute of Cancer Research, London, UK., Jones C; Division of Molecular Pathology, Institute of Cancer Research, London, UK., Grill J; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Université Paris-Saclay, Villejuif, France.; U981, Molecular Predictors and New Targets in Oncology, Team Genomics and Oncogenesis of Pediatric Brain Tumors, INSERM, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Ajlil Y; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Université Paris-Saclay, Villejuif, France.; U981, Molecular Predictors and New Targets in Oncology, Team Genomics and Oncogenesis of Pediatric Brain Tumors, INSERM, Gustave Roussy, Université Paris-Saclay, Villejuif, France., von Bueren AO; Department of Pediatrics, Obstetrics and Gynecology, Division of Pediatric Hematology and Oncology, University Hospital Geneva, Geneva, Switzerland.; Cancer Research Platform for Pediatric Oncology and Hematology, Faculty of Medicine, Department of Pediatrics, Gynecology and Obstetrics, University of Geneva, Geneva, Switzerland., Karremann M; Department of Pediatric and Adolescent Medicine, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany., Hoffmann M; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany., Kramm CM; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany., Kwiecien R; Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany., Castel D; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Université Paris-Saclay, Villejuif, France.; U981, Molecular Predictors and New Targets in Oncology, Team Genomics and Oncogenesis of Pediatric Brain Tumors, INSERM, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Gielen GH; Institute of Neuropathology, DGNN Brain Tumor Reference Center, University of Bonn Medical Center, Bonn, Germany., Varlet P; Department of Neuropathology, GHU Paris-Psychiatrie et Neurosciences, Sainte-Anne Hospital, 1, Rue Cabanis, 75014, Paris, France.; Inserm, UMR 1266, IMA-Brain, Institut de Psychiatrie et Neurosciences de Paris, Paris, France. |
| Source: | Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Nov 18; Vol. 12 (1), pp. 176. Date of Electronic Publication: 2024 Nov 18. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2051-5960 |
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| DOI: | 10.1186/s40478-024-01881-1 |
