The Role of Phase Separation and Local Mobility in the Stabilization of a Lyophilized IgG2 Formulation.
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| Title: | The Role of Phase Separation and Local Mobility in the Stabilization of a Lyophilized IgG2 Formulation. |
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| Authors: | Lay-Fortenbery A; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky, 40526, USA.; Preclinical Development, Merck & Co. Inc., Rahway, New Jersey, USA., Holcomb RE; Legacy Biodesign LLC, Johnstown, Colorado, 80534, USA. rholcomb@legacybiodesign.com.; Department of Chemistry, Colorado State University, Fort Collins, Colorado, 80523, USA. rholcomb@legacybiodesign.com., Henry CS; Department of Chemistry, Colorado State University, Fort Collins, Colorado, 80523, USA., Manning MC; Legacy Biodesign LLC, Johnstown, Colorado, 80534, USA.; Department of Chemistry, Colorado State University, Fort Collins, Colorado, 80523, USA., Munson EJ; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky, 40526, USA. munsone@purdue.edu.; Department of Industrial and Molecular Pharmaceutics, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, Robert E. Heine Pharmacy Building, West Lafayette, IN, 47907, USA. munsone@purdue.edu. |
| Source: | AAPS PharmSciTech [AAPS PharmSciTech] 2024 Nov 19; Vol. 25 (8), pp. 268. Date of Electronic Publication: 2024 Nov 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: United States NLM ID: 100960111 Publication Model: Electronic Cited Medium: Internet ISSN: 1530-9932 (Electronic) Linking ISSN: 15309932 NLM ISO Abbreviation: AAPS PharmSciTech Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1530-9932 |
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| DOI: | 10.1208/s12249-024-02984-7 |
