Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma.

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Bibliographic Details
Title: Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma.
Authors: Chen YJ; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Cancer Biology & Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Iyer SV; Cancer Biology & Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hsieh DC; Tri-Institutional PhD Program in Chemical Biology, The Rockefeller University, New York, NY, USA.; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA., Li B; Structure Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Elias HK; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; National Institutes of Health, Bethesda, MD, USA., Wang T; Cancer Biology & Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Neuroscience Program, Weill Cornell Medicine Graduate School of Medical Sciences, New York, NY, USA., Li J; Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ganbold M; Cancer Biology & Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lien MC; Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Peng YC; Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Xie XP; Cancer Biology & Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Jayewickreme CD; Cancer Biology & Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., van den Brink MRM; City of Hope, Los Angeles, CA, USA., Brady SF; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA., Lim SK; KOBIOLABS, Inc., Seongnam-si, South Korea., Parada LF; Cancer Biology & Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. paradal@mskcc.org.; Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA. paradal@mskcc.org.; Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. paradal@mskcc.org.; Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. paradal@mskcc.org.
Source: Nature [Nature] 2024 Dec; Vol. 636 (8042), pp. 466-473. Date of Electronic Publication: 2024 Nov 20.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4687
DOI:10.1038/s41586-024-08224-z