Integrative proteomic analyses across common cardiac diseases yield mechanistic insights and enhanced prediction.

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Title: Integrative proteomic analyses across common cardiac diseases yield mechanistic insights and enhanced prediction.
Authors: Schuermans A; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Faculty of Medicine, KU Leuven, Leuven, Belgium., Pournamdari AB; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Lee J; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Bhukar R; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Ganesh S; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Darosa N; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Small AM; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Medicine Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Yu Z; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Hornsby W; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Koyama S; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Januzzi JL; Baim Institute for Clinical Research, Boston, MA, USA.; Division of Cardiology, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Honigberg MC; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA, USA. mhonigberg@mgh.harvard.edu.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. mhonigberg@mgh.harvard.edu.; Division of Cardiology, Massachusetts General Hospital, Boston, MA, USA. mhonigberg@mgh.harvard.edu.; Department of Medicine, Harvard Medical School, Boston, MA, USA. mhonigberg@mgh.harvard.edu., Natarajan P; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA, USA. pnatarajan@mgh.harvard.edu.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. pnatarajan@mgh.harvard.edu.; Division of Cardiology, Massachusetts General Hospital, Boston, MA, USA. pnatarajan@mgh.harvard.edu.; Department of Medicine, Harvard Medical School, Boston, MA, USA. pnatarajan@mgh.harvard.edu.
Source: Nature cardiovascular research [Nat Cardiovasc Res] 2024 Dec; Vol. 3 (12), pp. 1516-1530. Date of Electronic Publication: 2024 Nov 21.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 9918284280206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2731-0590 (Electronic) Linking ISSN: 27310590 NLM ISO Abbreviation: Nat Cardiovasc Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2731-0590
DOI:10.1038/s44161-024-00567-0