Nascent transcript O-MAP reveals the molecular architecture of a single-locus subnuclear compartment built by RBM20 and the TTN RNA.

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Title: Nascent transcript O-MAP reveals the molecular architecture of a single-locus subnuclear compartment built by RBM20 and the TTN RNA.
Authors: Kania EE; Department of Pharmacology, University of Washington, Seattle, WA, USA.; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.; Present affiliations: Shape Therapeutics, Seattle, WA (E.E.K); Department of Biology, Massachusetts Institute of Technology (D.M. M.); Department of Computer Science and Software Engineering, California Polytechnic State University at San Luis Obispo (B.H); Department of Stem Cell and Regenerative Medicine, and the Eli and Edyth Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California (C.E.M.)., Fenix A; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.; Departments of Laboratory Medicine and Pathology, Bioengineering, and Medicine/Cardiology, University of Washington, Seattle, WA, USA., Marciniak DM; Department of Pharmacology, University of Washington, Seattle, WA, USA.; Present affiliations: Shape Therapeutics, Seattle, WA (E.E.K); Department of Biology, Massachusetts Institute of Technology (D.M. M.); Department of Computer Science and Software Engineering, California Polytechnic State University at San Luis Obispo (B.H); Department of Stem Cell and Regenerative Medicine, and the Eli and Edyth Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California (C.E.M.)., Lin Q; Department of Pharmacology, University of Washington, Seattle, WA, USA.; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Bianchi S; Molecular Biotechnology Center 'Guido Tarone', Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy., Hristov B; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Present affiliations: Shape Therapeutics, Seattle, WA (E.E.K); Department of Biology, Massachusetts Institute of Technology (D.M. M.); Department of Computer Science and Software Engineering, California Polytechnic State University at San Luis Obispo (B.H); Department of Stem Cell and Regenerative Medicine, and the Eli and Edyth Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California (C.E.M.)., Li S; Department of Pharmacology, University of Washington, Seattle, WA, USA.; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA., Camplisson CK; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Fields R; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Beliveau BJ; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Schweppe DK; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Noble WS; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Paul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, USA., Ong SE; Department of Pharmacology, University of Washington, Seattle, WA, USA., Bertero A; Molecular Biotechnology Center 'Guido Tarone', Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy., Murry CE; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.; Departments of Laboratory Medicine and Pathology, Bioengineering, and Medicine/Cardiology, University of Washington, Seattle, WA, USA.; Present affiliations: Shape Therapeutics, Seattle, WA (E.E.K); Department of Biology, Massachusetts Institute of Technology (D.M. M.); Department of Computer Science and Software Engineering, California Polytechnic State University at San Luis Obispo (B.H); Department of Stem Cell and Regenerative Medicine, and the Eli and Edyth Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California (C.E.M.)., Shechner DM; Department of Pharmacology, University of Washington, Seattle, WA, USA.; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 13. Date of Electronic Publication: 2024 Nov 13.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2024.11.05.622011