Trial protocol for SiroSkin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients.

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Title: Trial protocol for SiroSkin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients.
Authors: Dousset L; Frazer Institute, The University of Queensland, Experimental Dermatology Group, Brisbane, Australia. l.dousset@uq.edu.au.; Faculty of Medicine, The University of Queensland, Brisbane, Australia. l.dousset@uq.edu.au., Chambers DC; Faculty of Medicine, The University of Queensland, Brisbane, Australia.; Queensland Lung Transplant Service, The Prince Charles Hospital, Brisbane, Australia., Webster A; NHMRC Clinical Trials Centre, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.; Department of Renal Medicine and Transplantation, Westmead Hospital, Westmead, NSW, Australia.; Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Isbel N; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia., Campbell S; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia., Duarte C; Melanoma and Skin Cancer Research Centre, Monash University, Melbourne, VIC, Australia., Collins L; Population Health, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Damian D; Department of Dermatology, The University of Sydney at Royal Prince Alfred Hospital, Camperdown, NSW, Australia.; Melanoma Institute Australia, Sydney, Australia., Tseng A; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia.; Department of Nephrology and Transplantation Services, Prince Charles Hospital, Brisbane, Australia.; Department of Dermatology, Princess Alexandra Hospital, Brisbane, Australia., Karlsen E; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia.; Department of Nephrology and Transplantation Services, Prince Charles Hospital, Brisbane, Australia.; Department of Dermatology, Princess Alexandra Hospital, Brisbane, Australia., Ilinsky OV; Department of Nephrology and Transplantation Services, Prince Charles Hospital, Brisbane, Australia.; Department of Dermatology, Princess Alexandra Hospital, Brisbane, Australia., Brown S; Frazer Institute, The University of Queensland, Experimental Dermatology Group, Brisbane, Australia., Schaider H; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia.; Department of Dermatology, Princess Alexandra Hospital, Brisbane, Australia.; Frazer Institute, The University of Queensland, Dermatology Research Centre, Brisbane, Australia., Soyer HP; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia.; Department of Dermatology, Princess Alexandra Hospital, Brisbane, Australia.; Frazer Institute, The University of Queensland, Dermatology Research Centre, Brisbane, Australia., Ospino DA; Melanoma and Skin Cancer Research Centre, Monash University, Melbourne, VIC, Australia., Hogarth S; Melanoma and Skin Cancer Research Centre, Monash University, Melbourne, VIC, Australia., Chong AH; Skin Health Institute, Carlton, VIC, Australia., Mar V; Department of Dermatology, Alfred Hospital, The School of Translational Medicine, Monash University, Melbourne, Australia., McKenzie S; Faculty of Medicine, The University of Queensland, Brisbane, Australia.; Advanced Heart Failure and Cardiac Transplant Unit, The Prince Charles Hospital, Chermside, QLD, Australia., Gin D; Department of Dermatology, Alfred Hospital, The School of Translational Medicine, Monash University, Melbourne, Australia., Fernandez-Penas P; Department of Dermatology, Westmead Hospital, The University of Sydney, Westmead, NSW, Australia., Kern JS; Department of Dermatology, Alfred Hospital, The School of Translational Medicine, Monash University, Melbourne, Australia., Loewe K; Melanoma and Skin Cancer Research Centre, Monash University, Melbourne, VIC, Australia., Roy E; Frazer Institute, The University of Queensland, Experimental Dermatology Group, Brisbane, Australia., Herschtal A; School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia., Khosrotehrani K; Frazer Institute, The University of Queensland, Experimental Dermatology Group, Brisbane, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, Australia.; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia.; Department of Nephrology and Transplantation Services, Prince Charles Hospital, Brisbane, Australia.; Department of Dermatology, Princess Alexandra Hospital, Brisbane, Australia.
Source: Trials [Trials] 2024 Nov 22; Vol. 25 (1), pp. 789. Date of Electronic Publication: 2024 Nov 22.
Publication Type: Clinical Trial Protocol; Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Trial protocol for SiroSkin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients.
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  Data: <searchLink fieldCode="AU" term="%22Dousset+L%22">Dousset L</searchLink>; Frazer Institute, The University of Queensland, Experimental Dermatology Group, Brisbane, Australia. l.dousset@uq.edu.au.; Faculty of Medicine, The University of Queensland, Brisbane, Australia. l.dousset@uq.edu.au.<br /><searchLink fieldCode="AU" term="%22Chambers+DC%22">Chambers DC</searchLink>; Faculty of Medicine, The University of Queensland, Brisbane, Australia.; Queensland Lung Transplant Service, The Prince Charles Hospital, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Webster+A%22">Webster A</searchLink>; NHMRC Clinical Trials Centre, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.; Department of Renal Medicine and Transplantation, Westmead Hospital, Westmead, NSW, Australia.; Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Isbel+N%22">Isbel N</searchLink>; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Campbell+S%22">Campbell S</searchLink>; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Duarte+C%22">Duarte C</searchLink>; Melanoma and Skin Cancer Research Centre, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Collins+L%22">Collins L</searchLink>; Population Health, QIMR Berghofer Medical Research Institute, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Damian+D%22">Damian D</searchLink>; Department of Dermatology, The University of Sydney at Royal Prince Alfred Hospital, Camperdown, NSW, Australia.; Melanoma Institute Australia, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Tseng+A%22">Tseng A</searchLink>; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia.; Department of Nephrology and Transplantation Services, Prince Charles Hospital, Brisbane, Australia.; Department of Dermatology, Princess Alexandra Hospital, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Karlsen+E%22">Karlsen E</searchLink>; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia.; Department of Nephrology and Transplantation Services, Prince Charles Hospital, Brisbane, Australia.; Department of Dermatology, Princess Alexandra Hospital, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Ilinsky+OV%22">Ilinsky OV</searchLink>; Department of Nephrology and Transplantation Services, Prince Charles Hospital, Brisbane, Australia.; Department of Dermatology, Princess Alexandra Hospital, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Brown+S%22">Brown S</searchLink>; Frazer Institute, The University of Queensland, Experimental Dermatology Group, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Schaider+H%22">Schaider H</searchLink>; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia.; Department of Dermatology, Princess Alexandra Hospital, Brisbane, Australia.; Frazer Institute, The University of Queensland, Dermatology Research Centre, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Soyer+HP%22">Soyer HP</searchLink>; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia.; Department of Dermatology, Princess Alexandra Hospital, Brisbane, Australia.; Frazer Institute, The University of Queensland, Dermatology Research Centre, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Ospino+DA%22">Ospino DA</searchLink>; Melanoma and Skin Cancer Research Centre, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Hogarth+S%22">Hogarth S</searchLink>; Melanoma and Skin Cancer Research Centre, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Chong+AH%22">Chong AH</searchLink>; Skin Health Institute, Carlton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Mar+V%22">Mar V</searchLink>; Department of Dermatology, Alfred Hospital, The School of Translational Medicine, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22McKenzie+S%22">McKenzie S</searchLink>; Faculty of Medicine, The University of Queensland, Brisbane, Australia.; Advanced Heart Failure and Cardiac Transplant Unit, The Prince Charles Hospital, Chermside, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Gin+D%22">Gin D</searchLink>; Department of Dermatology, Alfred Hospital, The School of Translational Medicine, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Fernandez-Penas+P%22">Fernandez-Penas P</searchLink>; Department of Dermatology, Westmead Hospital, The University of Sydney, Westmead, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Kern+JS%22">Kern JS</searchLink>; Department of Dermatology, Alfred Hospital, The School of Translational Medicine, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Loewe+K%22">Loewe K</searchLink>; Melanoma and Skin Cancer Research Centre, Monash University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Roy+E%22">Roy E</searchLink>; Frazer Institute, The University of Queensland, Experimental Dermatology Group, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Herschtal+A%22">Herschtal A</searchLink>; School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Khosrotehrani+K%22">Khosrotehrani K</searchLink>; Frazer Institute, The University of Queensland, Experimental Dermatology Group, Brisbane, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, Australia.; Department of Nephrology and Transplantation Services, Princess Alexandra Hospital, Brisbane, Australia.; Department of Nephrology and Transplantation Services, Prince Charles Hospital, Brisbane, Australia.; Department of Dermatology, Princess Alexandra Hospital, Brisbane, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101263253%22">Trials</searchLink> [Trials] 2024 Nov 22; Vol. 25 (1), pp. 789. <i>Date of Electronic Publication: </i>2024 Nov 22.
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