Childhood-onset lupus nephritis is characterized by complex interactions between kidney stroma and infiltrating immune cells.

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Title: Childhood-onset lupus nephritis is characterized by complex interactions between kidney stroma and infiltrating immune cells.
Authors: Danaher P; Bruker Spatial Biology, Seattle, WA 98109, USA., Hasle N; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195, USA., Nguyen ED; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195, USA.; Seattle Children's Research Institute, Seattle, WA 98101, USA., Roberts JE; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195, USA.; Seattle Children's Research Institute, Seattle, WA 98101, USA., Rosenwasser N; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195, USA.; Seattle Children's Research Institute, Seattle, WA 98101, USA., Rickert C; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Hsieh EWY; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.; Pediatrics, Section of Allergy and Immunology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Hayward K; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195, USA.; Seattle Children's Research Institute, Seattle, WA 98101, USA., Okamura DM; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195, USA.; Seattle Children's Research Institute, Seattle, WA 98101, USA., Alpers CE; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA 98195, USA., Reed RC; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA 98195, USA., Baxter SK; Sonoma Biotherapeutics, Seattle, WA 98119, USA., Jackson SW; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195, USA.; Seattle Children's Research Institute, Seattle, WA 98101, USA.; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA 98195, USA.
Source: Science translational medicine [Sci Transl Med] 2024 Nov 27; Vol. 16 (775), pp. eadl1666. Date of Electronic Publication: 2024 Nov 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1946-6242
DOI:10.1126/scitranslmed.adl1666