GLP-1 and GIP agonism has no direct actions in human hepatocytes or hepatic stellate cells.
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| Title: | GLP-1 and GIP agonism has no direct actions in human hepatocytes or hepatic stellate cells. |
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| Authors: | da Silva Lima N; Department of Physiology, CIMUS, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain., Cabaleiro A; Department of Physiology, CIMUS, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain., Novoa E; Department of Physiology, CIMUS, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain.; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), Madrid, Spain., Riobello C; Department of Biochemistry and Molecular Biology, CIMUS, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain., Knerr PJ; Indiana Biosciences Research Institute, Indianapolis, IN, USA., He Y; Indiana Biosciences Research Institute, Indianapolis, IN, USA., Esquinas-Román EM; Department of Biochemistry and Molecular Biology, CIMUS, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain., González-García I; Department of Physiology, CIMUS, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain.; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), Madrid, Spain., Prevot V; Laboratory of Development and Plasticity of the Neuroendocrine Brain, Lille Neuroscience & Cognition, UMR-S 1172, Univ. Lille, Inserm, CHU Lille, European Genomic Institute for Diabetes (EGID), 59000, Lille, France., Schwaninger M; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Lübeck, Germany., Dieguez C; Department of Physiology, CIMUS, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain.; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), Madrid, Spain., López M; Department of Physiology, CIMUS, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain.; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), Madrid, Spain., Müller TD; Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Helmholtz Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Walther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany., Varela-Rey M; Department of Biochemistry and Molecular Biology, CIMUS, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain., Douros JD; Novo Nordisk Research Center Indianapolis, Indianapolis, IN, USA., Nogueiras R; Department of Physiology, CIMUS, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain. ruben.nogueiras@usc.es.; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), Madrid, Spain. ruben.nogueiras@usc.es.; Galician Agency of Innovation (GAIN), Xunta de Galicia, Santiago de Compostela, Spain. ruben.nogueiras@usc.es. |
| Source: | Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Nov 28; Vol. 81 (1), pp. 468. Date of Electronic Publication: 2024 Nov 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1420-9071 |
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| DOI: | 10.1007/s00018-024-05507-6 |
