Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function.
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| Title: | Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function. |
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| Authors: | Kordon SP; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.; Neuroscience Institute, The University of Chicago, Chicago, IL, USA.; Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA.; Center for Mechanical Excitability, University of Chicago, Chicago, IL, USA., Cechova K; Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA., Bandekar SJ; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.; Neuroscience Institute, The University of Chicago, Chicago, IL, USA.; Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA.; Center for Mechanical Excitability, University of Chicago, Chicago, IL, USA., Leon K; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.; Neuroscience Institute, The University of Chicago, Chicago, IL, USA.; Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA., Dutka P; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.; Department of Structural Biology, Genentech, South San Francisco, CA, USA., Siffer G; Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA., Kossiakoff AA; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA., Vafabakhsh R; Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA. reza.vafabakhsh@northwestern.edu., Araç D; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA. arac@uchicago.edu.; Neuroscience Institute, The University of Chicago, Chicago, IL, USA. arac@uchicago.edu.; Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA. arac@uchicago.edu.; Center for Mechanical Excitability, University of Chicago, Chicago, IL, USA. arac@uchicago.edu. |
| Source: | Nature communications [Nat Commun] 2024 Dec 04; Vol. 15 (1), pp. 10545. Date of Electronic Publication: 2024 Dec 04. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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