Homeostatic microglia initially seed and activated microglia later reshape amyloid plaques in Alzheimer's Disease.

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Title: Homeostatic microglia initially seed and activated microglia later reshape amyloid plaques in Alzheimer's Disease.
Authors: Baligács N; Centre for Brain and Disease Research, Flanders Institute for Biotechnology (VIB), Leuven, Belgium.; Department of Neurosciences and Leuven Brain Institute, KU Leuven, Leuven, Belgium., Albertini G; Centre for Brain and Disease Research, Flanders Institute for Biotechnology (VIB), Leuven, Belgium.; Department of Neurosciences and Leuven Brain Institute, KU Leuven, Leuven, Belgium., Borrie SC; Centre for Brain and Disease Research, Flanders Institute for Biotechnology (VIB), Leuven, Belgium.; Department of Neurosciences and Leuven Brain Institute, KU Leuven, Leuven, Belgium., Serneels L; Centre for Brain and Disease Research, Flanders Institute for Biotechnology (VIB), Leuven, Belgium.; Department of Neurosciences and Leuven Brain Institute, KU Leuven, Leuven, Belgium., Pridans C; University of Edinburgh Centre for Inflammation Research, Edinburgh, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, UK., Balusu S; Centre for Brain and Disease Research, Flanders Institute for Biotechnology (VIB), Leuven, Belgium.; Department of Neurosciences and Leuven Brain Institute, KU Leuven, Leuven, Belgium., De Strooper B; Centre for Brain and Disease Research, Flanders Institute for Biotechnology (VIB), Leuven, Belgium. b.destrooper@ukdri.ucl.ac.uk.; Department of Neurosciences and Leuven Brain Institute, KU Leuven, Leuven, Belgium. b.destrooper@ukdri.ucl.ac.uk.; UK Dementia Research Institute at UCL, University College London, London, UK. b.destrooper@ukdri.ucl.ac.uk.
Source: Nature communications [Nat Commun] 2024 Dec 05; Vol. 15 (1), pp. 10634. Date of Electronic Publication: 2024 Dec 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-024-54779-w