In Situ Tracking of TCRβ Isoforms for Detection of T Cell Clonality: Implication for Precision Diagnosis and Targeted Immunotherapy of T-Cell Neoplasms.

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Title: In Situ Tracking of TCRβ Isoforms for Detection of T Cell Clonality: Implication for Precision Diagnosis and Targeted Immunotherapy of T-Cell Neoplasms.
Authors: Manipadam MT; Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK., Marra A; Department of Medicine and Surgery, Laboratory of Molecular Medicine and Biotechnology, University Campus Bio-Medico of Rome, Rome, Italy.; Institute of Translational Pharmacology, National Research Council of Italy (CNR), Rome, Italy., Ramsay A; Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK., Padmasri S; Department Research Pathology, Cancer Institute, University College London, London, UK., Gosh A; Department Research Pathology, Cancer Institute, University College London, London, UK., Neves M; Department Research Pathology, Cancer Institute, University College London, London, UK., Bailey C; Department of Clinical Haematology, University College Hospitals London, London, UK., Pomplun S; Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK., Maciocia P; Research Department of Haematology, Cancer Institute, University College London, London, UK.; Autolus Ltd, London, UK., Cwynarski K; Department of Clinical Haematology, University College Hospitals London, London, UK., Ferrari M; Autolus Ltd, London, UK., Lao-Siriex P; Autolus Ltd, London, UK., Piris M; Pathology Department, lnstituto de lnvestigacion Sanitaria Fundacion Jimenez Diaz, Madrid, Spain., Falini B; Institute of Haematology and Center for Haemato-Oncological Research (CREO), University of Perugia and Santa Maria della Misericordia Hospital, Perugia, Italy., Linch D; Research Department of Haematology, Cancer Institute, University College London, London, UK., Rosenwald A; Institute of Pathology, University of Würzburg, Würzburg, Germany., Pule M; Research Department of Haematology, Cancer Institute, University College London, London, UK., Zamò A; Institute of Pathology, University of Würzburg, Würzburg, Germany., Marafioti T; Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK.; Department Research Pathology, Cancer Institute, University College London, London, UK.
Source: Hematological oncology [Hematol Oncol] 2025 Jan; Vol. 43 (1), pp. e70018.
Publication Type: Letter
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8307268 Publication Model: Print Cited Medium: Internet ISSN: 1099-1069 (Electronic) Linking ISSN: 02780232 NLM ISO Abbreviation: Hematol Oncol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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ISSN:1099-1069
DOI:10.1002/hon.70018