Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus.

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Title: Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus.
Authors: Matera A; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland., Compagnion AC; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland., Pedicone C; Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mt. Sinai, New York, NY, USA; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kotah JM; Department of Biomedical Sciences, Section Molecular Neurobiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Ivanov A; Core Unit Bioinformatics, Berlin Institute of Health, Charité-Universitätsmedizin Berlin, Berlin, Germany., Monsorno K; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland., Labouèbe G; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland., Leggio L; Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy., Pereira-Iglesias M; Achucarro Basque Center for Neuroscience, Barrio Sarriena s/n, Leioa, Spain; Department of Neuroscience, University of the Basque Country EHU/UPV, Barrio Sarriena s/n, Leioa, Spain., Beule D; Core Unit Bioinformatics, Berlin Institute of Health, Charité-Universitätsmedizin Berlin, Berlin, Germany., Mansuy-Aubert V; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland., Williams TL; Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Iraci N; Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy., Sierra A; Achucarro Basque Center for Neuroscience, Barrio Sarriena s/n, Leioa, Spain; Department of Biochemistry and Molecular Biology, University of the Basque Country EHU/UPV, Barrio Sarriena, Leioa, Spain; Ikerbasque Foundation, Bilbao, Spain., Marro SG; Institute for Regenerative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Neurosciences, Black Family Stem Cell Institute, Icahn School of Medicine at Mt. Sinai, New York, NY, USA., Goate AM; Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mt. Sinai, New York, NY, USA; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Eggen BJL; Department of Biomedical Sciences, Section Molecular Neurobiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Kerr WG; Institute for Regenerative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Microbiology & Immunology, SUNY Upstate Medical University, Syracuse, NY, USA; Department of Pediatrics, SUNY Upstate Medical University, Syracuse, NY, USA., Paolicelli RC; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland. Electronic address: rosachiara.paolicelli@unil.ch.
Source: Immunity [Immunity] 2025 Jan 14; Vol. 58 (1), pp. 197-217.e13. Date of Electronic Publication: 2024 Dec 09.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-4180
DOI:10.1016/j.immuni.2024.11.003