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IL-23R is a senescence-linked circulating and tissue biomarker of aging.

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Title: IL-23R is a senescence-linked circulating and tissue biomarker of aging.
Authors: Carver CM; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Rodriguez SL; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Atkinson EJ; Department of Quantitative Health Sciences, Division of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, MN, USA., Dosch AJ; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Asmussen NC; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Gomez PT; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA., Leitschuh EA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Espindola-Netto JM; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Jeganathan KB; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA., Whaley MG; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA., Kamenecka TM; Department of Molecular Medicine, UF Scripps Institute, The Scripps Research Institute, Scripps Florida, Jupiter, FL, USA., Baker DJ; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA., Haak AJ; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA., LeBrasseur NK; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Schafer MJ; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA. schafer.marissa@mayo.edu.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA. schafer.marissa@mayo.edu.; Department of Neurology, Mayo Clinic, Rochester, MN, USA. schafer.marissa@mayo.edu.; Department of Neuroscience, Mayo Clinic, Rochester, MN, USA. schafer.marissa@mayo.edu.
Source: Nature aging [Nat Aging] 2025 Feb; Vol. 5 (2), pp. 291-305. Date of Electronic Publication: 2024 Dec 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group US Country of Publication: United States NLM ID: 101773306 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-8465 (Electronic) Linking ISSN: 26628465 NLM ISO Abbreviation: Nat Aging Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: IL-23R is a senescence-linked circulating and tissue biomarker of aging.
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  Data: <searchLink fieldCode="AU" term="%22Carver+CM%22">Carver CM</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Rodriguez+SL%22">Rodriguez SL</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Atkinson+EJ%22">Atkinson EJ</searchLink>; Department of Quantitative Health Sciences, Division of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Dosch+AJ%22">Dosch AJ</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Asmussen+NC%22">Asmussen NC</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Gomez+PT%22">Gomez PT</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Leitschuh+EA%22">Leitschuh EA</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Espindola-Netto+JM%22">Espindola-Netto JM</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Jeganathan+KB%22">Jeganathan KB</searchLink>; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Whaley+MG%22">Whaley MG</searchLink>; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Kamenecka+TM%22">Kamenecka TM</searchLink>; Department of Molecular Medicine, UF Scripps Institute, The Scripps Research Institute, Scripps Florida, Jupiter, FL, USA.<br /><searchLink fieldCode="AU" term="%22Baker+DJ%22">Baker DJ</searchLink>; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Haak+AJ%22">Haak AJ</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22LeBrasseur+NK%22">LeBrasseur NK</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Schafer+MJ%22">Schafer MJ</searchLink>; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA. schafer.marissa@mayo.edu.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA. schafer.marissa@mayo.edu.; Department of Neurology, Mayo Clinic, Rochester, MN, USA. schafer.marissa@mayo.edu.; Department of Neuroscience, Mayo Clinic, Rochester, MN, USA. schafer.marissa@mayo.edu.
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  Data: <searchLink fieldCode="JN" term="%22101773306%22">Nature aging</searchLink> [Nat Aging] 2025 Feb; Vol. 5 (2), pp. 291-305. <i>Date of Electronic Publication: </i>2024 Dec 10.
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