A selective small-molecule agonist of G protein-gated inwardly-rectifying potassium channels reduces epileptiform activity in mouse models of tumor-associated and provoked seizures.
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| Title: | A selective small-molecule agonist of G protein-gated inwardly-rectifying potassium channels reduces epileptiform activity in mouse models of tumor-associated and provoked seizures. |
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| Authors: | Rifkin RA; Department of Neurology, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: rr3302@cumc.columbia.edu., Wu X; Department of Neurological Surgery, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: xw2013@cumc.columbia.edu., Pereira B; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, 630 West 168th Street, Mailbox 23, New York, NY, 10032, USA. Electronic address: bp2401@cumc.columbia.edu., Gill BJ; Department of Neurological Surgery, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: bjg2140@cumc.columbia.edu., Merricks EM; Department of Neurology, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: em3217@cumc.columbia.edu., Michalak AJ; Department of Neurology, New York University Grossman School of Medicine, 222 East 41st Street, 14th Floor New York, NY, 10017, USA. Electronic address: andrew.michalak@nyulangone.org., Goldberg AR; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, 630 West 168th Street, Mailbox 23, New York, NY, 10032, USA. Electronic address: ag3311@cumc.columbia.edu., Humala N; Department of Neurological Surgery, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: nh2560@cumc.columbia.edu., Dovas A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, 630 West 168th Street, Mailbox 23, New York, NY, 10032, USA. Electronic address: ad3106@cumc.columbia.edu., Rai G; National Center for Advancing Translational Sciences, National Institutes of Health, 9609 Medical Center Drive, Rockville, MD, 20850-9793, USA. Electronic address: bantukallug@mail.nih.gov., McKhann GM; Department of Neurological Surgery, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: gm317@cumc.columbia.edu., Slesinger PA; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029-5674, USA. Electronic address: Paul.Slesinger@mssm.edu., Canoll P; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, 630 West 168th Street, Mailbox 23, New York, NY, 10032, USA. Electronic address: pc561@cumc.columbia.edu., Schevon C; Department of Neurology, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: cas2044@cumc.columbia.edu. |
| Source: | Neuropharmacology [Neuropharmacology] 2025 Mar 01; Vol. 265, pp. 110259. Date of Electronic Publication: 2024 Dec 09. |
| Publication Type: | Journal Article; Research Support, U.S. Gov't, P.H.S.; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39662702 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A selective small-molecule agonist of G protein-gated inwardly-rectifying potassium channels reduces epileptiform activity in mouse models of tumor-associated and provoked seizures. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Rifkin+RA%22">Rifkin RA</searchLink>; Department of Neurology, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: rr3302@cumc.columbia.edu.<br /><searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: xw2013@cumc.columbia.edu.<br /><searchLink fieldCode="AU" term="%22Pereira+B%22">Pereira B</searchLink>; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, 630 West 168th Street, Mailbox 23, New York, NY, 10032, USA. Electronic address: bp2401@cumc.columbia.edu.<br /><searchLink fieldCode="AU" term="%22Gill+BJ%22">Gill BJ</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: bjg2140@cumc.columbia.edu.<br /><searchLink fieldCode="AU" term="%22Merricks+EM%22">Merricks EM</searchLink>; Department of Neurology, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: em3217@cumc.columbia.edu.<br /><searchLink fieldCode="AU" term="%22Michalak+AJ%22">Michalak AJ</searchLink>; Department of Neurology, New York University Grossman School of Medicine, 222 East 41st Street, 14th Floor New York, NY, 10017, USA. Electronic address: andrew.michalak@nyulangone.org.<br /><searchLink fieldCode="AU" term="%22Goldberg+AR%22">Goldberg AR</searchLink>; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, 630 West 168th Street, Mailbox 23, New York, NY, 10032, USA. Electronic address: ag3311@cumc.columbia.edu.<br /><searchLink fieldCode="AU" term="%22Humala+N%22">Humala N</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: nh2560@cumc.columbia.edu.<br /><searchLink fieldCode="AU" term="%22Dovas+A%22">Dovas A</searchLink>; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, 630 West 168th Street, Mailbox 23, New York, NY, 10032, USA. Electronic address: ad3106@cumc.columbia.edu.<br /><searchLink fieldCode="AU" term="%22Rai+G%22">Rai G</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, 9609 Medical Center Drive, Rockville, MD, 20850-9793, USA. Electronic address: bantukallug@mail.nih.gov.<br /><searchLink fieldCode="AU" term="%22McKhann+GM%22">McKhann GM</searchLink>; Department of Neurological Surgery, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: gm317@cumc.columbia.edu.<br /><searchLink fieldCode="AU" term="%22Slesinger+PA%22">Slesinger PA</searchLink>; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029-5674, USA. Electronic address: Paul.Slesinger@mssm.edu.<br /><searchLink fieldCode="AU" term="%22Canoll+P%22">Canoll P</searchLink>; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, 630 West 168th Street, Mailbox 23, New York, NY, 10032, USA. Electronic address: pc561@cumc.columbia.edu.<br /><searchLink fieldCode="AU" term="%22Schevon+C%22">Schevon C</searchLink>; Department of Neurology, Columbia University Irving Medical Center, 710 West 168th Street, New York, NY, 10032-3784, USA. Electronic address: cas2044@cumc.columbia.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220236217%22">Neuropharmacology</searchLink> [Neuropharmacology] 2025 Mar 01; Vol. 265, pp. 110259. <i>Date of Electronic Publication: </i>2024 Dec 09. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, U.S. Gov't, P.H.S.; Research Support, U.S. Gov't, Non-P.H.S. – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Pergamon+Press%22">Pergamon Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0236217 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-7064 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200283908%22">00283908 </searchLink><i>NLM ISO Abbreviation: </i>Neuropharmacology <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39662702 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.neuropharm.2024.110259 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 110259 Titles: – TitleFull: A selective small-molecule agonist of G protein-gated inwardly-rectifying potassium channels reduces epileptiform activity in mouse models of tumor-associated and provoked seizures. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Rifkin RA – PersonEntity: Name: NameFull: Wu X – PersonEntity: Name: NameFull: Pereira B – PersonEntity: Name: NameFull: Gill BJ – PersonEntity: Name: NameFull: Merricks EM – PersonEntity: Name: NameFull: Michalak AJ – PersonEntity: Name: NameFull: Goldberg AR – PersonEntity: Name: NameFull: Humala N – PersonEntity: Name: NameFull: Dovas A – PersonEntity: Name: NameFull: Rai G – PersonEntity: Name: NameFull: McKhann GM – PersonEntity: Name: NameFull: Slesinger PA – PersonEntity: Name: NameFull: Canoll P – PersonEntity: Name: NameFull: Schevon C IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: 2025 Mar 01 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1873-7064 Numbering: – Type: volume Value: 265 Titles: – TitleFull: Neuropharmacology Type: main |
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