How to build the virtual cell with artificial intelligence: Priorities and opportunities.

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Title: How to build the virtual cell with artificial intelligence: Priorities and opportunities.
Authors: Bunne C; Department of Computer Science, Stanford University, Stanford, CA, USA; Genentech, South San Francisco, CA, USA; Chan Zuckerberg Initiative, Redwood City, CA, USA; School of Computer and Communication Sciences and School of Life Sciences, EPFL, Lausanne, Switzerland., Roohani Y; Department of Computer Science, Stanford University, Stanford, CA, USA; Chan Zuckerberg Initiative, Redwood City, CA, USA; Arc Institute, Palo Alto, CA, USA., Rosen Y; Department of Computer Science, Stanford University, Stanford, CA, USA; Chan Zuckerberg Initiative, Redwood City, CA, USA., Gupta A; Chan Zuckerberg Initiative, Redwood City, CA, USA; Department of Protein Science, Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden., Zhang X; Department of Computer Science, Stanford University, Stanford, CA, USA; Chan Zuckerberg Initiative, Redwood City, CA, USA; Department of Bioengineering, Stanford University, Stanford, CA, USA., Roed M; Department of Computer Science, Stanford University, Stanford, CA, USA; Chan Zuckerberg Initiative, Redwood City, CA, USA., Alexandrov T; Department of Pharmacology, University of California, San Diego, San Diego, CA, USA; Department of Bioengineering, University of California, San Diego, San Diego, CA, USA., AlQuraishi M; Department of Bioengineering, University of California, San Diego, San Diego, CA, USA., Brennan P; Chan Zuckerberg Initiative, Redwood City, CA, USA., Burkhardt DB; Cellarity, Somerville, MA, USA., Califano A; Department of Systems Biology, Columbia University, New York, NY, USA; Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA; Chan Zuckerberg Biohub, New York, NY, USA., Cool J; Chan Zuckerberg Initiative, Redwood City, CA, USA., Dernburg AF; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Ewing K; Chan Zuckerberg Initiative, Redwood City, CA, USA., Fox EB; Department of Computer Science, Stanford University, Stanford, CA, USA; Department of Statistics, Stanford University, Stanford, CA, USA; Chan Zuckerberg Biohub, San Francisco, CA, USA., Haury M; Chan Zuckerberg Institute for Advanced Biological Imaging, Redwood City, CA, USA., Herr AE; Chan Zuckerberg Biohub, San Francisco, CA, USA; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Horvitz E; Microsoft Research, Redmond, WA, USA., Hsu PD; Arc Institute, Palo Alto, CA, USA; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA., Jain V; Google Research, Mountain View, CA, USA., Johnson GR; NewLimit, San Francisco, CA, USA., Kalil T; Schmidt Futures, New York, NY, USA., Kelley DR; Calico Life Sciences LLC, San Francisco, CA, USA., Kelley SO; Chan Zuckerberg Biohub, Chicago, IL, USA; Northwestern University, Evanston, IL, USA., Kreshuk A; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany., Mitchison T; Department of Systems Biology, Harvard Medical School, Boston, MA, USA., Otte S; Chan Zuckerberg Institute for Advanced Biological Imaging, Redwood City, CA, USA., Shendure J; Department of Genome Sciences, University of Washington, Seattle, WA, USA; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA; Seattle Hub for Synthetic Biology, Seattle, WA, USA; Howard Hughes Medical Institute, Seattle, WA, USA., Sofroniew NJ; EvolutionaryScale, PBC, New York, NY, USA., Theis F; Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany; School of Computing, Information and Technology, Technical University of Munich, Munich, Germany; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany., Theodoris CV; Gladstone Institute of Cardiovascular Disease, Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Upadhyayula S; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA; Chan Zuckerberg Biohub, San Francisco, CA, USA; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Valer M; Chan Zuckerberg Initiative, Redwood City, CA, USA., Wang B; Department of Computer Science, University of Toronto, Toronto, ON, Canada; Vector Institute, Toronto, ON, Canada., Xing E; Carnegie Mellon University, School of Computer Science, Pittsburgh, PA, USA; Mohamed Bin Zayed University of Artificial Intelligence, Abu Dhabi, United Arab Emirates., Yeung-Levy S; Department of Computer Science, Stanford University, Stanford, CA, USA; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA., Zitnik M; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA; Kempner Institute for the Study of Natural and Artificial Intelligence, Harvard University, Cambridge, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Karaletsos T; Chan Zuckerberg Initiative, Redwood City, CA, USA. Electronic address: tkaraletsos@chanzuckerberg.com., Regev A; Genentech, South San Francisco, CA, USA. Electronic address: regev.aviv@gene.com., Lundberg E; Chan Zuckerberg Initiative, Redwood City, CA, USA; Department of Protein Science, Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden; Department of Bioengineering, Stanford University, Stanford, CA, USA; Department of Pathology, Stanford University, Stanford, CA, USA. Electronic address: emmalu@stanford.edu., Leskovec J; Department of Computer Science, Stanford University, Stanford, CA, USA; Chan Zuckerberg Initiative, Redwood City, CA, USA. Electronic address: jure@cs.stanford.edu., Quake SR; Chan Zuckerberg Initiative, Redwood City, CA, USA; Department of Bioengineering, Stanford University, Stanford, CA, USA; Department of Applied Physics, Stanford University, Stanford, CA, USA. Electronic address: steve@czbiohub.org.
Source: Cell [Cell] 2024 Dec 12; Vol. 187 (25), pp. 7045-7063.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-4172
DOI:10.1016/j.cell.2024.11.015