GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis.

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Title: GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis.
Authors: Cocozza G; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy. Electronic address: germana.cocozza@uniroma1.it., Busdraghi LM; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy., Chece G; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy., Menini A; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy., Ceccanti M; Department of Human Neuroscience, Sapienza University, Rome, Italy., Libonati L; Department of Human Neuroscience, Sapienza University, Rome, Italy., Cambieri C; Department of Human Neuroscience, Sapienza University, Rome, Italy., Fiorentino F; Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Rome, Italy., Rotili D; Department of Science, Roma Tre University, Rome, Italy., Scavizzi F; EMMA CNR, Monterotondo, Italy., Raspa M; EMMA CNR, Monterotondo, Italy., Aronica E; Amsterdam UMC, University of Amsterdam, Department of (Neuro)Pathology, Amsterdam Neuroscience, Meibergdreef 9, Amsterdam, the Netherlands., Inghilleri M; Department of Human Neuroscience, Sapienza University, Rome, Italy; IRCCS Neuromed, Pozzilli, Italy., Garofalo S; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy., Limatola C; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy; IRCCS Neuromed, Pozzilli, Italy. Electronic address: cristina.limatola@uniroma1.it.
Source: Brain, behavior, and immunity [Brain Behav Immun] 2025 Feb; Vol. 124, pp. 280-293. Date of Electronic Publication: 2024 Dec 11.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1090-2139
DOI:10.1016/j.bbi.2024.12.010