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GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis.

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Title: GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis.
Authors: Cocozza G; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy. Electronic address: germana.cocozza@uniroma1.it., Busdraghi LM; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy., Chece G; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy., Menini A; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy., Ceccanti M; Department of Human Neuroscience, Sapienza University, Rome, Italy., Libonati L; Department of Human Neuroscience, Sapienza University, Rome, Italy., Cambieri C; Department of Human Neuroscience, Sapienza University, Rome, Italy., Fiorentino F; Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Rome, Italy., Rotili D; Department of Science, Roma Tre University, Rome, Italy., Scavizzi F; EMMA CNR, Monterotondo, Italy., Raspa M; EMMA CNR, Monterotondo, Italy., Aronica E; Amsterdam UMC, University of Amsterdam, Department of (Neuro)Pathology, Amsterdam Neuroscience, Meibergdreef 9, Amsterdam, the Netherlands., Inghilleri M; Department of Human Neuroscience, Sapienza University, Rome, Italy; IRCCS Neuromed, Pozzilli, Italy., Garofalo S; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy., Limatola C; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy; IRCCS Neuromed, Pozzilli, Italy. Electronic address: cristina.limatola@uniroma1.it.
Source: Brain, behavior, and immunity [Brain Behav Immun] 2025 Feb; Vol. 124, pp. 280-293. Date of Electronic Publication: 2024 Dec 11.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE
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  Data: GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Cocozza+G%22">Cocozza G</searchLink>; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy. Electronic address: germana.cocozza@uniroma1.it.<br /><searchLink fieldCode="AU" term="%22Busdraghi+LM%22">Busdraghi LM</searchLink>; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Chece+G%22">Chece G</searchLink>; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Menini+A%22">Menini A</searchLink>; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ceccanti+M%22">Ceccanti M</searchLink>; Department of Human Neuroscience, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Libonati+L%22">Libonati L</searchLink>; Department of Human Neuroscience, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cambieri+C%22">Cambieri C</searchLink>; Department of Human Neuroscience, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Fiorentino+F%22">Fiorentino F</searchLink>; Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Rotili+D%22">Rotili D</searchLink>; Department of Science, Roma Tre University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Scavizzi+F%22">Scavizzi F</searchLink>; EMMA CNR, Monterotondo, Italy.<br /><searchLink fieldCode="AU" term="%22Raspa+M%22">Raspa M</searchLink>; EMMA CNR, Monterotondo, Italy.<br /><searchLink fieldCode="AU" term="%22Aronica+E%22">Aronica E</searchLink>; Amsterdam UMC, University of Amsterdam, Department of (Neuro)Pathology, Amsterdam Neuroscience, Meibergdreef 9, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Inghilleri+M%22">Inghilleri M</searchLink>; Department of Human Neuroscience, Sapienza University, Rome, Italy; IRCCS Neuromed, Pozzilli, Italy.<br /><searchLink fieldCode="AU" term="%22Garofalo+S%22">Garofalo S</searchLink>; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Limatola+C%22">Limatola C</searchLink>; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy; IRCCS Neuromed, Pozzilli, Italy. Electronic address: cristina.limatola@uniroma1.it.
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  Data: <searchLink fieldCode="JN" term="%228800478%22">Brain, behavior, and immunity</searchLink> [Brain Behav Immun] 2025 Feb; Vol. 124, pp. 280-293. <i>Date of Electronic Publication: </i>2024 Dec 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8800478 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2139 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208891591%22">08891591 </searchLink><i>NLM ISO Abbreviation: </i>Brain Behav Immun <i>Subsets: </i>MEDLINE
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              Text: 2025 Feb
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