Alzheimer's disease-associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain.

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Title: Alzheimer's disease-associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain.
Authors: Readhead BP; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, Arizona, USA., Mastroeni DF; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, Arizona, USA., Wang Q; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, Arizona, USA., Sierra MA; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York, USA., de Ávila C; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, Arizona, USA., Jimoh TO; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Haure-Mirande JV; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Atanasoff KE; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Nolz J; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, Arizona, USA., Suazo C; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, Arizona, USA., Barton NJ; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Orszulak AR; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Chigas SM; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Tran K; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Mirza A; Department of Microbiology and Physiological Systems, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Ryon K; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York, USA., Proszynski J; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York, USA., Najjar D; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York, USA., Dudley JT; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, Arizona, USA., Liu STH; Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Gandy S; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Ehrlich ME; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Alsop E; Division of Neurogenomics, The Translational Genomics Research Institute, Phoenix, Arizona, USA., Antone J; Division of Neurogenomics, The Translational Genomics Research Institute, Phoenix, Arizona, USA., Reiman R; Division of Neurogenomics, The Translational Genomics Research Institute, Phoenix, Arizona, USA., Funk C; Institute for Systems Biology, Seattle, Washington, USA., Best RL; Serimmune, Inc, Goleta, California, USA., Jhatro M; Serimmune, Inc, Goleta, California, USA., Kamath K; Serimmune, Inc, Goleta, California, USA., Shon J; Serimmune, Inc, Goleta, California, USA., Kowalik TF; Department of Microbiology and Physiological Systems, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA., Liang WS; Division of Neurogenomics, The Translational Genomics Research Institute, Phoenix, Arizona, USA., Serrano GE; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Sun City, Arizona, USA., Beach TG; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Sun City, Arizona, USA., Van Keuren-Jensen K; Division of Neurogenomics, The Translational Genomics Research Institute, Phoenix, Arizona, USA., Mason CE; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York, USA., Chan Y; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Lim ET; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.; Department of Medicine, Division of Innate Immunity, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Tortorella D; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Reiman EM; Banner Alzheimer's Institute, Phoenix, Arizona, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Jan; Vol. 21 (1), pp. e14401. Date of Electronic Publication: 2024 Dec 19.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1552-5279
DOI:10.1002/alz.14401