Coupling antigens from multiple subtypes of influenza can broaden antibody and T cell responses.

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Title: Coupling antigens from multiple subtypes of influenza can broaden antibody and T cell responses.
Authors: Mallajosyula V; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA, USA., Chakraborty S; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA, USA.; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA, USA., Sola E; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA, USA., Fong RF; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA, USA., Shankar V; Program in Immunology, Stanford University School of Medicine, Stanford, CA, USA., Gao F; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA, USA., Burrell AR; Department of Pediatrics, Division of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Gupta N; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA, USA., Wagar LE; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA, USA.; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA., Mischel PS; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA., Capasso R; Division of Sleep Surgery, Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA., Staat MA; Department of Pediatrics, Division of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Chien YH; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA, USA.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA., Dekker CL; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA., Wang TT; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA, USA.; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA, USA., Davis MM; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA, USA.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA.
Source: Science (New York, N.Y.) [Science] 2024 Dec 20; Vol. 386 (6728), pp. 1389-1395. Date of Electronic Publication: 2024 Dec 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1095-9203
DOI:10.1126/science.adi2396