Piperine induces cellular stresses, apoptosis, and cytotoxicity via JNK signaling and has concentration-dependently additive or synergistic effects with sorafenib in hepatocellular carcinoma: an in-vitro study.
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| Title: | Piperine induces cellular stresses, apoptosis, and cytotoxicity via JNK signaling and has concentration-dependently additive or synergistic effects with sorafenib in hepatocellular carcinoma: an in-vitro study. |
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| Authors: | Sayilan Ozgun G; Department of Medical Biochemistry, Trakya University School of Medicine, Edirne, 22030, Turkey. gulbensayilanozgun@gmail.com., Ozgun E; Department of Medical Biochemistry, Trakya University School of Medicine, Edirne, 22030, Turkey., Karabas T; Department of Medical Biochemistry, Trakya University School of Medicine, Edirne, 22030, Turkey., Suer Gokmen S; Department of Medical Biochemistry, Trakya University School of Medicine, Edirne, 22030, Turkey., Eskiocak S; Department of Medical Biochemistry, Trakya University School of Medicine, Edirne, 22030, Turkey. |
| Source: | Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Jun; Vol. 398 (6), pp. 7017-7025. Date of Electronic Publication: 2024 Dec 21. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-1912 |
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| DOI: | 10.1007/s00210-024-03725-0 |