Proteome profiling of cerebrospinal fluid using machine learning shows a unique protein signature associated with APOE4 genotype.
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| Title: | Proteome profiling of cerebrospinal fluid using machine learning shows a unique protein signature associated with APOE4 genotype. |
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| Authors: | Shvetcov A; Translational Dementia Research Group, Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, Sydney, NSW, Australia.; Department of Psychological Medicine, Sydney Children's Hospital Network, Sydney, NSW, Australia.; Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia., Thomson S; Translational Dementia Research Group, Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, Sydney, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Cho AN; Human Brain Microphysiology Systems Group, School of Biomedical Engineering, Faculty of Engineering, The University of Sydney, Sydney, NSW, Australia., Wilkins HM; University of Kansas Alzheimer's Disease Research Centre, Kansas City, KS, USA.; Department of Biochemistry and Molecular Biology, University of Kansas Medical Centre, Kansas City, KS, USA.; Department of Neurology, University of Kansas Medical Centre, Kansas City, KS, USA., Reed JH; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.; Autoimmunity and Amyloidosis Research Group, Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, Sydney, NSW, Australia., Swerdlow RH; University of Kansas Alzheimer's Disease Research Centre, Kansas City, KS, USA.; Department of Biochemistry and Molecular Biology, University of Kansas Medical Centre, Kansas City, KS, USA.; Department of Neurology, University of Kansas Medical Centre, Kansas City, KS, USA.; Department of Molecular and Integrative Physiology, University of Kansas Medical Centre, Kansas City, KS, USA., Brown DA; Neuroinflammation Research Group, Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, Sydney, NSW, Australia.; Department of Immunopathology, Institute for Clinical Pathology and Medical Research-New South Wales Health Pathology, Sydney, NSW, Australia.; Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Finney CA; Translational Dementia Research Group, Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, Sydney, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia. |
| Corporate Authors: | Alzheimer's Disease Neuroimaging Initiative |
| Source: | Aging cell [Aging Cell] 2025 Apr; Vol. 24 (4), pp. e14439. Date of Electronic Publication: 2024 Dec 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1474-9726 |
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| DOI: | 10.1111/acel.14439 |
