Functional differences between rodent and human PD-1 linked to evolutionary divergence.

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Title: Functional differences between rodent and human PD-1 linked to evolutionary divergence.
Authors: Masubuchi T; Department of Cell and Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Chen L; Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China., Marcel N; Department of Molecular Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Wen GA; Department of Cell and Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Caron C; Department of Pathology, University of California San Diego, La Jolla, CA 92093, USA., Zhang J; Department of Cell and Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Zhao Y; Department of Cell and Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Morris GP; Department of Pathology, University of California San Diego, La Jolla, CA 92093, USA., Chen X; Department of Neurosciences, University of California San Diego, La Jolla, CA 92093, USA., Hedrick SM; Department of Molecular Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Lu LF; Department of Molecular Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Wu C; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Zou Z; Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China., Bui JD; Department of Pathology, University of California San Diego, La Jolla, CA 92093, USA., Hui E; Department of Cell and Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.
Source: Science immunology [Sci Immunol] 2025 Jan 03; Vol. 10 (103), pp. eads6295. Date of Electronic Publication: 2025 Jan 03.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2470-9468
DOI:10.1126/sciimmunol.ads6295