Comprehensive histopathological analysis of gastric cancer in European and Latin America populations reveals differences in PDL1, HER2, p53 and MUC6 expression.
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| Title: | Comprehensive histopathological analysis of gastric cancer in European and Latin America populations reveals differences in PDL1, HER2, p53 and MUC6 expression. |
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| Authors: | Martínez-Ciarpaglini C; Department of Pathology, Hospital Clinico Universitario, INCLIVA, Biomedical Research Institute, University of Valencia, Valencia, Spain., Barros R; Ipatimup, Institute of Molecular Pathology and Immunology of the University of Porto, Rua Júlio Amaral de Carvalho 45, 4200-135, Porto, Portugal.; i3S-Instituto de Investigação e Inovação em Saúde, Universidade Do Porto, Porto, Portugal.; Faculty of Medicine of the University of Porto, Porto, Portugal.; Department of Pathology, Unidade Local de Saúde São João, Porto, Portugal., Caballero C; Department of Pathology, GENPAT, Asunción, Paraguay., Boggino H; Department of Pathology, GENPAT, Asunción, Paraguay., Alarcón-Molero L; Department of Pathology, Hospital Clinico Universitario, INCLIVA, Biomedical Research Institute, University of Valencia, Valencia, Spain.; Department of Pathology, Hospital General de Valdepeñas, Valdepeñas, Spain., Peleteiro B; Hospital Epidemiology Center, University Hospital Center of São João, Porto, Portugal.; Department of Public Health and Forensic Sciences, and Medical Education, Faculty of Medicine, University of Porto, Porto, Portugal.; EPIUnit-Institute of Public Health, University of Porto, Porto, Portugal.; Laboratory for Integrative and Translational Research in Population Health (ITR), University of Porto, Porto, Portugal., Ruiz-García E; Departamento de Tumores de Tubo Digestivo, Instituto Nacional de Cancerología, Mexico City, México.; Laboratorio de Medicina Traslacional, Instituto Nacional de Cancerología, Mexico City, México., Fernandez-Figueroa E; Núcleo B de Innovación en Medicina de Precisión, Instituto Nacional de Medicina Genómica, Mexico City, México., Herrera-Goepfert R; Departamento de Patología Quirúrgica, Instituto Nacional de Cancerología, Mexico City, México., Díaz-Romero C; Departamento de Oncología Médica, Instituto Nacional de Cancerología, Mexico City, México., Ferreira R; Ipatimup, Institute of Molecular Pathology and Immunology of the University of Porto, Rua Júlio Amaral de Carvalho 45, 4200-135, Porto, Portugal.; Microbes & Cancer. i3S, Instituto de Investigação e Inovação em Saúde, , Rua Alfredo Allen, 208, 4200-135, Porto, Portugal., Groen-van Schooten TS; Department of Medical Oncology, Amsterdam University Medical Center (UMC) Location Vrije Universiteit Amsterdam, Amsterdam, Netherlands.; Cancer Biology and Immunology, Cancer Center Amsterdam, Amsterdam, Netherlands.; Oncode Institute, Amsterdam, The Netherlands., Gauna C; Medical Oncology Department, Instituto de Previsión Social, Asunción, Paraguay., Pereira R; Medical Oncology Department, Instituto de Previsión Social, Asunción, Paraguay., Cantero D; Department of Gastroenterology, Instituto de Previsión Social, Asunción, Paraguay., Lezcano H; Pathology Department, Instituto de Previsión Social, Asunción, Paraguay., Esteso F; Medical Oncology Department, Instituto Alexander Fleming, Buenos Aires, Argentina., O Connor J; Medical Oncology Department, Instituto Alexander Fleming, Buenos Aires, Argentina., Riquelme A; Department of Gastroenterology, Faculty of MedicineCenter for Prevention and Control of Cancer (CECAN), Pontificia Universidad Catolica de Chile, Santiago, Chile., Owen GI; Faculty of Biological Sciences & Faculty of Medicine, Millennium Institute for Immunology and ImmunotherapyCenter for Prevention and Control of Cancer (CECAN), Advance Center for Chronic Disease (ACCDIS), Pontificia Universidad Católica de Chile, Santiago, Chile., Garrido M; Centro de Oncología de Precisión, Universidad Mayor, Santiago, Chile., Roa JC; Department of Pathology. Faculty of Medicine. Pontificia, Universidad Católica de Chile Santiago, Santiago, Chile., Ruiz-Pace F; Oncology Data Science, Valld`Hebron Institute of Oncology, Barcelona, Spain., Vivancos A; Cancer Genomics Lab, Valld`Hebron Institute of Oncology, Barcelona, Spain., Diez-García M; Medical Oncology Department, Valld`Hebron Institute of Oncology, Barcelona, Spain., Alsina M; Medical Oncology Department, Valld`Hebron Institute of Oncology, Barcelona, Spain.; Hospital Universitario de Navarra, Navarrabiomed-IdiSNA, Pamplona, Spain., Matito J; Cancer Genomics Lab, Valld`Hebron Institute of Oncology, Barcelona, Spain., Martin A; Cancer Genomics Lab, Valld`Hebron Institute of Oncology, Barcelona, Spain., Gómez M; Cancer Genomics Lab, Valld`Hebron Institute of Oncology, Barcelona, Spain., Castillo E; Cancer Genomics Lab, Valld`Hebron Institute of Oncology, Barcelona, Spain., Vila M; Cancer Genomics Lab, Valld`Hebron Institute of Oncology, Barcelona, Spain., Santos-Antunes J; Department of Gastroenterology, Unidade Local de Saúde São João, Porto, Portugal., Costa A; Department of Oncology, Unidade Local de Saúde São João, Porto, Portugal., Lordick F; Department of Medicine (Oncology, Gastroenterology, Hepatology, and Pulmonology), Comprehensive Cancer Center Central Germany (CCCG), University of Leipzig Medical Center, Leipzig, Germany., Farrés J; Anaxomics Biotech, S.L. Barcelona, Barcelona, Spain., Palomar-De Lucas B; Department of Medical Oncology, Hospital Clinico Universitario, INCLIVA, Biomedical Research Institute, University of Valencia, Avenida Menendez Pelayo nro 4 accesorio, Valencia, Spain., Cabeza-Segura M; Department of Medical Oncology, Hospital Clinico Universitario, INCLIVA, Biomedical Research Institute, University of Valencia, Avenida Menendez Pelayo nro 4 accesorio, Valencia, Spain., Villagrasa R; Department of Gastroenterology, Hospital Clínico Universitario de Valencia, Valencia, Spain., Jimenez-Martí E; Department of Medical Oncology, Hospital Clinico Universitario, INCLIVA, Biomedical Research Institute, University of Valencia, Avenida Menendez Pelayo nro 4 accesorio, Valencia, Spain., Miralles-Marco A; Department of Medical Oncology, Hospital Clinico Universitario, INCLIVA, Biomedical Research Institute, University of Valencia, Avenida Menendez Pelayo nro 4 accesorio, Valencia, Spain., Dienstmann R; Oncology Data Science, Valld`Hebron Institute of Oncology, Barcelona, Spain., Derks S; Department of Medical Oncology, Amsterdam University Medical Center (UMC) Location Vrije Universiteit Amsterdam, Amsterdam, Netherlands.; Cancer Biology and Immunology, Cancer Center Amsterdam, Amsterdam, Netherlands.; Oncode Institute, Amsterdam, The Netherlands., Figueiredo C; Ipatimup, Institute of Molecular Pathology and Immunology of the University of Porto, Rua Júlio Amaral de Carvalho 45, 4200-135, Porto, Portugal.; i3S-Instituto de Investigação e Inovação em Saúde, Universidade Do Porto, Porto, Portugal.; Faculty of Medicine of the University of Porto, Porto, Portugal., Cervantes A; Department of Medical Oncology, Hospital Clinico Universitario, INCLIVA, Biomedical Research Institute, University of Valencia, Avenida Menendez Pelayo nro 4 accesorio, Valencia, Spain.; Department of Gastroenterology, Hospital Clínico Universitario de Valencia, Valencia, Spain.; CiberOnc. Carlos III Institute, Madrid, Spain., Carneiro F; Ipatimup, Institute of Molecular Pathology and Immunology of the University of Porto, Rua Júlio Amaral de Carvalho 45, 4200-135, Porto, Portugal.; i3S-Instituto de Investigação e Inovação em Saúde, Universidade Do Porto, Porto, Portugal.; Faculty of Medicine of the University of Porto, Porto, Portugal.; Department of Pathology, Unidade Local de Saúde São João, Porto, Portugal., Fleitas-Kanonnikoff T; Department of Medical Oncology, Hospital Clinico Universitario, INCLIVA, Biomedical Research Institute, University of Valencia, Avenida Menendez Pelayo nro 4 accesorio, Valencia, Spain. tfleitas@incliva.es. |
| Source: | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association [Gastric Cancer] 2025 Mar; Vol. 28 (2), pp. 160-173. Date of Electronic Publication: 2025 Jan 05. |
| Publication Type: | Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 100886238 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1436-3305 (Electronic) Linking ISSN: 14363291 NLM ISO Abbreviation: Gastric Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1436-3305 |
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| DOI: | 10.1007/s10120-024-01578-3 |
