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Trastuzumab Plus Pertuzumab Versus Cetuximab Plus Irinotecan in Patients With RAS/BRAF Wild-Type, HER2-Positive, Metastatic Colorectal Cancer (S1613): A Randomized Phase II Trial.

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Title: Trastuzumab Plus Pertuzumab Versus Cetuximab Plus Irinotecan in Patients With RAS/BRAF Wild-Type, HER2-Positive, Metastatic Colorectal Cancer (S1613): A Randomized Phase II Trial.
Authors: Raghav KPS; MD Anderson Cancer Center, Houston, TX., Guthrie KA; SWOG Statistics and Data Management Center, Seattle, WA.; Fred Hutchinson Cancer Center, Seattle, WA., Tan B Jr; Washington University Siteman Cancer Center, St Louis, MO., Denlinger CS; Fox Chase Cancer Center, Philadelphia, PA., Fakih M; City of Hope National Medical Center, Duarte, CA., Overman MJ; MD Anderson Cancer Center, Houston, TX., Dasari NA; MD Anderson Cancer Center, Houston, TX., Corum LR; University of Kansas Cancer Center-MCA Rural MU NCORP/Olathe Health Cancer Center, Olathe, KS., Hicks LG; Baptist Health Cancer Research Network/Baptist Health Lexington, Lexington, KY., Patel MS; CORA NCORP, CommonSpirit Health Research Institute/Cancer Center at Saint Joseph's, Phoenix, AZ., Esparaz BT; Heartland Cancer Research NCORP/Cancer Care Specialists of Illinois, Decatur, IL., Kazmi SM; University of Texas Southwestern Medical Center/Parkland Memorial Hospital, Dallas, TX., Alluri N; Pacific Cancer Research Consortium NCORP/St Luke's Cancer Institute, Boise, ID., Colby S; SWOG Statistics and Data Management Center, Seattle, WA.; Fred Hutchinson Cancer Center, Seattle, WA., Gholami S; UC Davis Comprehensive Cancer Center, Sacramento, CA., Gold PJ; Swedish Cancer Institute, Seattle, WA., Chiorean EG; Fred Hutchinson Cancer Center, Seattle, WA.; University of Washington School of Medicine, Seattle, WA., Kopetz S; MD Anderson Cancer Center, Houston, TX., Hochster HS; Rutgers-Cancer Institute, New Brunswick, NJ., Philip PA; Wayne State University/Henry Ford Cancer Institute, Detroit, MI.
Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2025 Apr 10; Vol. 43 (11), pp. 1348-1357. Date of Electronic Publication: 2025 Jan 06.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study; Comparative Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Trastuzumab Plus Pertuzumab Versus Cetuximab Plus Irinotecan in Patients With RAS/BRAF Wild-Type, HER2-Positive, Metastatic Colorectal Cancer (S1613): A Randomized Phase II Trial.
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  Data: <searchLink fieldCode="AU" term="%22Raghav+KPS%22">Raghav KPS</searchLink>; MD Anderson Cancer Center, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Guthrie+KA%22">Guthrie KA</searchLink>; SWOG Statistics and Data Management Center, Seattle, WA.; Fred Hutchinson Cancer Center, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Tan+B+Jr%22">Tan B Jr</searchLink>; Washington University Siteman Cancer Center, St Louis, MO.<br /><searchLink fieldCode="AU" term="%22Denlinger+CS%22">Denlinger CS</searchLink>; Fox Chase Cancer Center, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Fakih+M%22">Fakih M</searchLink>; City of Hope National Medical Center, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Overman+MJ%22">Overman MJ</searchLink>; MD Anderson Cancer Center, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Dasari+NA%22">Dasari NA</searchLink>; MD Anderson Cancer Center, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Corum+LR%22">Corum LR</searchLink>; University of Kansas Cancer Center-MCA Rural MU NCORP/Olathe Health Cancer Center, Olathe, KS.<br /><searchLink fieldCode="AU" term="%22Hicks+LG%22">Hicks LG</searchLink>; Baptist Health Cancer Research Network/Baptist Health Lexington, Lexington, KY.<br /><searchLink fieldCode="AU" term="%22Patel+MS%22">Patel MS</searchLink>; CORA NCORP, CommonSpirit Health Research Institute/Cancer Center at Saint Joseph's, Phoenix, AZ.<br /><searchLink fieldCode="AU" term="%22Esparaz+BT%22">Esparaz BT</searchLink>; Heartland Cancer Research NCORP/Cancer Care Specialists of Illinois, Decatur, IL.<br /><searchLink fieldCode="AU" term="%22Kazmi+SM%22">Kazmi SM</searchLink>; University of Texas Southwestern Medical Center/Parkland Memorial Hospital, Dallas, TX.<br /><searchLink fieldCode="AU" term="%22Alluri+N%22">Alluri N</searchLink>; Pacific Cancer Research Consortium NCORP/St Luke's Cancer Institute, Boise, ID.<br /><searchLink fieldCode="AU" term="%22Colby+S%22">Colby S</searchLink>; SWOG Statistics and Data Management Center, Seattle, WA.; Fred Hutchinson Cancer Center, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Gholami+S%22">Gholami S</searchLink>; UC Davis Comprehensive Cancer Center, Sacramento, CA.<br /><searchLink fieldCode="AU" term="%22Gold+PJ%22">Gold PJ</searchLink>; Swedish Cancer Institute, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Chiorean+EG%22">Chiorean EG</searchLink>; Fred Hutchinson Cancer Center, Seattle, WA.; University of Washington School of Medicine, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Kopetz+S%22">Kopetz S</searchLink>; MD Anderson Cancer Center, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Hochster+HS%22">Hochster HS</searchLink>; Rutgers-Cancer Institute, New Brunswick, NJ.<br /><searchLink fieldCode="AU" term="%22Philip+PA%22">Philip PA</searchLink>; Wayne State University/Henry Ford Cancer Institute, Detroit, MI.
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  Data: <searchLink fieldCode="JN" term="%228309333%22">Journal of clinical oncology : official journal of the American Society of Clinical Oncology</searchLink> [J Clin Oncol] 2025 Apr 10; Vol. 43 (11), pp. 1348-1357. <i>Date of Electronic Publication: </i>2025 Jan 06.
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  Data: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study; Comparative Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Clinical+Oncology%22">American Society of Clinical Oncology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8309333 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1527-7755 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220732183X%22">0732183X </searchLink><i>NLM ISO Abbreviation: </i>J Clin Oncol <i>Subsets: </i>MEDLINE
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