Same-Slide Spatial Multi-Omics Integration Reveals Tumor Virus-Linked Spatial Reorganization of the Tumor Microenvironment.

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Title: Same-Slide Spatial Multi-Omics Integration Reveals Tumor Virus-Linked Spatial Reorganization of the Tumor Microenvironment.
Authors: Yeo YY; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.; Program in Virology, Division of Medical Sciences, Harvard Medical School, Boston, MA, United States., Chang Y; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.; Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH, United States.; Department of Biomedical Informatics, College of Medicine, Ohio State University, Columbus, OH, United States., Qiu H; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Yiu SPT; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Michel HA; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.; Program in Virology, Division of Medical Sciences, Harvard Medical School, Boston, MA, United States., Wu W; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Jin X; Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH, United States.; Department of Biomedical Informatics, College of Medicine, Ohio State University, Columbus, OH, United States., Kure S; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States., Parmelee L; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Luo S; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Cramer P; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Lee JL; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Wang Y; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Yeung J; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Ahmar NE; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Simsek B; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Mohanna R; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Van Orden M; Translational Immunogenomics Lab, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States., Lu W; Translational Immunogenomics Lab, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States., Livak KJ; Translational Immunogenomics Lab, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States., Li S; Translational Immunogenomics Lab, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States., Shahryari J; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Kingsley L; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Al-Humadi RN; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Nasr S; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Nkosi D; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Sadigh S; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Rock P; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, United States., Frauenfeld L; Department of Pathology and Neuropathology, University Hospital and Comprehensive Cancer Center Tübingen, Tübingen, Germany., Kaufmann L; Department of Pathology and Neuropathology, University Hospital and Comprehensive Cancer Center Tübingen, Tübingen, Germany., Zhu B; Broad Institute of Harvard and MIT, Cambridge, MA, United States., Basak A; Broad Institute of Harvard and MIT, Cambridge, MA, United States., Dhanikonda N; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Chan CN; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Krull J; Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH, United States.; Department of Biomedical Informatics, College of Medicine, Ohio State University, Columbus, OH, United States., Cho YW; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, United States., Chen CY; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, United States., Lee JYJ; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Wang H; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States., Zhao B; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States., Loo LH; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Kim DM; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, United States., Boussiotis V; Department of Hematology Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Zhang B; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States., Shalek AK; Broad Institute of Harvard and MIT, Cambridge, MA, United States., Howitt B; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Signoretti S; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Schürch CM; Department of Pathology and Neuropathology, University Hospital and Comprehensive Cancer Center Tübingen, Tübingen, Germany., Hodi FS; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States., Burack WR; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, United States., Rodig SJ; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Ma Q; Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH, United States.; Department of Biomedical Informatics, College of Medicine, Ohio State University, Columbus, OH, United States., Jiang S; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.; Program in Virology, Division of Medical Sciences, Harvard Medical School, Boston, MA, United States.; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.; Broad Institute of Harvard and MIT, Cambridge, MA, United States.; Department of Pathology, Dana Farber Cancer Institute, Boston, MA, United States.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Dec 22. Date of Electronic Publication: 2024 Dec 22.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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