CXCL12 ameliorates neutrophilia and disease severity in SARS-CoV-2 infection.

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Title: CXCL12 ameliorates neutrophilia and disease severity in SARS-CoV-2 infection.
Authors: Zheng J; Department of Microbiology and Immunology and.; Center for Predictive Medicine, University of Louisville, Louisville, Kentucky, USA.; Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA., Dhakal H; Department of Microbiology and Immunology and., Qing E; Department of Microbiology and Immunology, Loyola University Chicago, Maywood, Illinois, USA., Shrestha R; Department of Microbiology and Immunology and.; Division of Immunotherapy, the Hiram C. Polk, Jr., MD, Department of Surgery, Immuno-Oncology Program, Brown Cancer Center and., Geller AE; Department of Microbiology and Immunology and.; Division of Immunotherapy, the Hiram C. Polk, Jr., MD, Department of Surgery, Immuno-Oncology Program, Brown Cancer Center and., Morrissey SM; Department of Microbiology and Immunology and.; Division of Immunotherapy, the Hiram C. Polk, Jr., MD, Department of Surgery, Immuno-Oncology Program, Brown Cancer Center and., Saxena D; Center for Predictive Medicine, University of Louisville, Louisville, Kentucky, USA., Hu X; Division of Immunotherapy, the Hiram C. Polk, Jr., MD, Department of Surgery, Immuno-Oncology Program, Brown Cancer Center and., Li H; Functional Immunomics Core, Brown Cancer Center, University of Louisville, Louisville, Kentucky, USA., Li H; Division of Immunotherapy, the Hiram C. Polk, Jr., MD, Department of Surgery, Immuno-Oncology Program, Brown Cancer Center and., Wilhelmsen K; BIOAGE Labs, Richmond, California, USA., Wendt LH; Institute for Clinical and Translational Science, University of Iowa, Iowa City, Iowa, USA., Klumpp K; BIOAGE Labs, Richmond, California, USA., Hume PS; Department of Medicine, Division of Pulmonary and Critical Care, National Jewish Health, Denver, Colorado, USA.; Department of Medicine, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Aurora, Colorado, USA., Janssen WJ; Department of Medicine, Division of Pulmonary and Critical Care, National Jewish Health, Denver, Colorado, USA.; Department of Medicine, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Aurora, Colorado, USA., Brody R; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Palmer KE; Center for Predictive Medicine, University of Louisville, Louisville, Kentucky, USA.; Department of Pharmacology and Toxicology and., Uriarte SM; Department of Oral Immunology and Infectious Diseases, University of Louisville, Louisville, Kentucky, USA., Ten Eyck P; Institute for Clinical and Translational Science, University of Iowa, Iowa City, Iowa, USA., Meyerholz DK; Department of Pathology, University of Iowa, Iowa City, Iowa, USA., Merchant ML; Department of Medicine, Division of Nephrology and Hypertension and., McLeish K; Department of Medicine, Division of Nephrology and Hypertension and., Gallagher T; Department of Microbiology and Immunology, Loyola University Chicago, Maywood, Illinois, USA., Huang J; Department of Anesthesiology and Perioperative Medicine, University of Louisville, Louisville, Kentucky, USA., Yan J; Department of Microbiology and Immunology and.; Division of Immunotherapy, the Hiram C. Polk, Jr., MD, Department of Surgery, Immuno-Oncology Program, Brown Cancer Center and., Perlman S; Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2025 Jan 07; Vol. 135 (4). Date of Electronic Publication: 2025 Jan 07.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1558-8238
DOI:10.1172/JCI188222