Endothelial-secreted Endocan activates PDGFRA and regulates vascularity and spatial phenotype in glioblastoma.
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| Title: | Endothelial-secreted Endocan activates PDGFRA and regulates vascularity and spatial phenotype in glioblastoma. |
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| Authors: | Bastola S; The Intellectual and Developmental Disabilities Research Center, The Semel Institute for Neuroscience and Human Behavior, and The Broad Stem Cell Research Center, The Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Pavlyukov MS; The Intellectual and Developmental Disabilities Research Center, The Semel Institute for Neuroscience and Human Behavior, and The Broad Stem Cell Research Center, The Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Sharma N; The Intellectual and Developmental Disabilities Research Center, The Semel Institute for Neuroscience and Human Behavior, and The Broad Stem Cell Research Center, The Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Ghochani Y; The Intellectual and Developmental Disabilities Research Center, The Semel Institute for Neuroscience and Human Behavior, and The Broad Stem Cell Research Center, The Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Nakano MA; Precision Medicine Institute, University of Alabama at Birmingham, Birmingham, AL, USA., Muthukrishnan SD; The Intellectual and Developmental Disabilities Research Center, The Semel Institute for Neuroscience and Human Behavior, and The Broad Stem Cell Research Center, The Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Yu SY; The Intellectual and Developmental Disabilities Research Center, The Semel Institute for Neuroscience and Human Behavior, and The Broad Stem Cell Research Center, The Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Kim MS; The Intellectual and Developmental Disabilities Research Center, The Semel Institute for Neuroscience and Human Behavior, and The Broad Stem Cell Research Center, The Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Johns Hopkins University School of Medicine, Baltimore, MD, USA., Sohrabi A; Department of Bioengineering, University of Texas at Austin, Austin, TX, USA., Biscola NP; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Yamashita D; Department of Neurosurgery, Ehime University Graduate School of Medicine, Shitsukawa 454, Toon, Ehime, Japan., Anufrieva KS; Center for Precision Genome Editing and Genetic Technologies for Biomedicine of Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia.; Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of the Federal Medical and Biological Agency, Moscow, Russia., Kovalenko TF; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Jung G; Department of Medicine, Center for Iron Disorders, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Ganz T; Department of Medicine, Center for Iron Disorders, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., O'Brien B; The Intellectual and Developmental Disabilities Research Center, The Semel Institute for Neuroscience and Human Behavior, and The Broad Stem Cell Research Center, The Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Kawaguchi R; The Intellectual and Developmental Disabilities Research Center, The Semel Institute for Neuroscience and Human Behavior, and The Broad Stem Cell Research Center, The Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Interdepartmental Program in Bioinformatics, Program in Neurogenetics, Department of Neurology and Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Qin Y; Interdepartmental Program in Bioinformatics, Program in Neurogenetics, Department of Neurology and Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Seidlits SK; Department of Bioengineering, University of Texas at Austin, Austin, TX, USA., Burlingame AL; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA., Oses-Prieto JA; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA., Havton LA; Departments of Neurology and Neuroscience, Icahn School of Medicine at Mount Sinai, James J Peters VA Medical Center, Bronx, NY, USA., Goldman SA; Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY, USA.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hjelmeland AB; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, USA., Nakano I; Department of Neurosurgery, Harada Hospital, Iruma, Saitama, Japan. dr.ichiro.nakano@gmail.com., Kornblum HI; The Intellectual and Developmental Disabilities Research Center, The Semel Institute for Neuroscience and Human Behavior, and The Broad Stem Cell Research Center, The Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. hkornblum@mednet.ucla.edu. |
| Source: | Nature communications [Nat Commun] 2025 Jan 07; Vol. 16 (1), pp. 471. Date of Electronic Publication: 2025 Jan 07. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-024-55487-1 |
