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Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution.

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Title: Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution.
Authors: Ma H; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore., Srivastava S; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ho SWT; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Xu C; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore., Lian BSX; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore., Ong X; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore., Tay ST; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore., Sheng T; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Lum HYJ; Department of Pathology, National University Hospital, Singapore, Singapore., Abdul Ghani SAB; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore., Chu Y; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Huang KK; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore., Goh YT; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Lee M; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore., Hagihara T; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore., Ng CSY; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore., Tan ALK; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore., Zhang Y; Department of Information Systems and Analytics, School of Computing, National University of Singapore, Singapore, Singapore., Ding Z; School of Medicine, Shanghai Jiao Tong University, Shanghai, China., Zhu F; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ng MSW; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Joseph CRC; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore., Chen H; MGI Tech Singapore Pte. Ltd., Singapore, Singapore., Li Z; MGI Tech Singapore Pte. Ltd., Singapore, Singapore., Zhao JJ; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore., Rha SY; Yonsei Cancer Center, Yonsei University Health System, Seoul, Republic of Korea.; Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Republic of Korea., Teh M; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Yeong J; Department of Pathology, National University Hospital, Singapore, Singapore.; Bioinformatics Institute, Agency for Science, Technology and Research, Singapore, Singapore., Yong WP; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Gastric Cancer Consortium, Singapore, Singapore., So JB; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Gastric Cancer Consortium, Singapore, Singapore.; Department of Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore.; Division of Surgical Oncology, National University Cancer Institute, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Sundar R; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore.; Singapore Gastric Cancer Consortium, Singapore, Singapore.; The N.1 Institute for Health, National University of Singapore, Singapore, Singapore., Tan P; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Singapore Gastric Cancer Consortium, Singapore, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Cellular and Molecular Research, National Cancer Centre, Singapore, Singapore.; Singhealth/Duke-NUS Institute of Precision Medicine, National Heart Centre Singapore, Singapore, Singapore.
Source: Cancer discovery [Cancer Discov] 2025 Apr 02; Vol. 15 (4), pp. 767-792.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
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Ltd., Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; MGI Tech Singapore Pte. Ltd., Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Zhao+JJ%22">Zhao JJ</searchLink>; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Rha+SY%22">Rha SY</searchLink>; Yonsei Cancer Center, Yonsei University Health System, Seoul, Republic of Korea.; Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Teh+M%22">Teh M</searchLink>; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Yeong+J%22">Yeong J</searchLink>; Department of Pathology, National University Hospital, Singapore, Singapore.; Bioinformatics Institute, Agency for Science, Technology and Research, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Yong+WP%22">Yong WP</searchLink>; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Gastric Cancer Consortium, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22So+JB%22">So JB</searchLink>; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Gastric Cancer Consortium, Singapore, Singapore.; Department of Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore.; Division of Surgical Oncology, National University Cancer Institute, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Sundar+R%22">Sundar R</searchLink>; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore.; Singapore Gastric Cancer Consortium, Singapore, Singapore.; The N.1 Institute for Health, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+P%22">Tan P</searchLink>; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Singapore Gastric Cancer Consortium, Singapore, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Cellular and Molecular Research, National Cancer Centre, Singapore, Singapore.; Singhealth/Duke-NUS Institute of Precision Medicine, National Heart Centre Singapore, Singapore, Singapore.
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              Text: 2025 Apr 02
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