Discovery of highly active kynureninases for cancer immunotherapy through protein language model.
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| Title: | Discovery of highly active kynureninases for cancer immunotherapy through protein language model. |
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| Authors: | Eom H; Department of Chemistry, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea., Park S; School of Biological Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea., Cho KS; Galux Inc, 1837 Nambusunhwan-ro, Gwanak-gu, Seoul 08738, Republic of Korea., Lee J; Department of Chemistry, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea., Kim H; School of Biological Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea., Kim S; School of Biological Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea., Yang J; Galux Inc, 1837 Nambusunhwan-ro, Gwanak-gu, Seoul 08738, Republic of Korea., Han YH; Galux Inc, 1837 Nambusunhwan-ro, Gwanak-gu, Seoul 08738, Republic of Korea., Lee J; Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.; School of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.; Arontier Co., 241 Gangnam-daero, Seocho-gu, Seoul 06735, Republic of Korea., Seok C; Artificial Intelligence Institute, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.; Institute of Molecular Biology and Genetics, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.; Department of Chemistry, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.; Galux Inc, 1837 Nambusunhwan-ro, Gwanak-gu, Seoul 08738, Republic of Korea., Lee MS; Department of Biomedical Sciences, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea.; Galux Inc, 1837 Nambusunhwan-ro, Gwanak-gu, Seoul 08738, Republic of Korea., Song WJ; Department of Chemistry, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea., Steinegger M; School of Biological Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.; Artificial Intelligence Institute, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.; Institute of Molecular Biology and Genetics, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea. |
| Source: | Nucleic acids research [Nucleic Acids Res] 2025 Jan 07; Vol. 53 (1). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1362-4962 |
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| DOI: | 10.1093/nar/gkae1245 |
