Prognostic impact of glucagon-like peptide-1 receptor (GLP1R) expression on cancer survival and its implications for GLP-1R agonist therapy: an integrative analysis across multiple tumor types.

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Title: Prognostic impact of glucagon-like peptide-1 receptor (GLP1R) expression on cancer survival and its implications for GLP-1R agonist therapy: an integrative analysis across multiple tumor types.
Authors: Ungvari Z; Vascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.; Stephenson Cancer Center, University of Oklahoma, Oklahoma City, OK, USA.; Oklahoma Center for Geroscience and Healthy Brain Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.; Department of Health Promotion Sciences, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.; International Training Program in Geroscience, Doctoral College/Institute of Preventive Medicine and Public Health, Semmelweis University, Budapest, Hungary., Bartha Á; Dept. of Bioinformatics, Semmelweis University, 1094, Budapest, Hungary., Ungvari A; Institute of Preventive Medicine and Public Health, Semmelweis University, Budapest, Hungary. Ungann2004@gmail.com., Fekete M; Institute of Preventive Medicine and Public Health, Semmelweis University, Budapest, Hungary., Bianchini G; Department of Medical Oncology, IRCCS Ospedale San Raffaele, Milan, Italy., Győrffy B; Dept. of Bioinformatics, Semmelweis University, 1094, Budapest, Hungary.; Dept. of Biophysics, Medical School, University of Pecs, H-7624, Pecs, Hungary.; Cancer Biomarker Research Group, Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, 1117, Budapest, Hungary.
Source: GeroScience [Geroscience] 2025 Jun; Vol. 47 (3), pp. 4413-4427. Date of Electronic Publication: 2025 Jan 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2509-2723
DOI:10.1007/s11357-024-01494-5