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Computational pathology applied to clinical colorectal cancer cohorts identifies immune and endothelial cell spatial patterns predictive of outcome.

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Title: Computational pathology applied to clinical colorectal cancer cohorts identifies immune and endothelial cell spatial patterns predictive of outcome.
Authors: Trahearn N; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.; UCL Cancer Institute, UCL, London, UK., Sakr C; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK., Banerjee A; Barts Cancer Institute, Queen Mary University of London, London, UK., Lee SH; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.; Systems Oncology group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, UK., Baker AM; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.; Barts Cancer Institute, Queen Mary University of London, London, UK., Kocher HM; Barts Cancer Institute, Queen Mary University of London, London, UK., Angerilli V; Department of Medicine (DIMED), University of Padua, Padua, Italy., Morano F; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Bergamo F; Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Maddalena G; Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.; Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, Padua, Italy., Intini R; Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Cremolini C; Computational Biology Research Centre, Human Technopole, Milan, Italy., Caravagna G; University of Triest, Triest, Italy., Graham T; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.; Barts Cancer Institute, Queen Mary University of London, London, UK., Pietrantonio F; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Lonardi S; Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Fassan M; Department of Medicine (DIMED), University of Padua, Padua, Italy.; Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Sottoriva A; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.; Computational Biology Research Centre, Human Technopole, Milan, Italy.
Source: The Journal of pathology [J Pathol] 2025 Feb; Vol. 265 (2), pp. 198-210.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 0204634 Publication Model: Print Cited Medium: Internet ISSN: 1096-9896 (Electronic) Linking ISSN: 00223417 NLM ISO Abbreviation: J Pathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Computational pathology applied to clinical colorectal cancer cohorts identifies immune and endothelial cell spatial patterns predictive of outcome.
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  Data: <searchLink fieldCode="AU" term="%22Trahearn+N%22">Trahearn N</searchLink>; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.; UCL Cancer Institute, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Sakr+C%22">Sakr C</searchLink>; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Banerjee+A%22">Banerjee A</searchLink>; Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Lee+SH%22">Lee SH</searchLink>; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.; Systems Oncology group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Baker+AM%22">Baker AM</searchLink>; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.; Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kocher+HM%22">Kocher HM</searchLink>; Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Angerilli+V%22">Angerilli V</searchLink>; Department of Medicine (DIMED), University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Morano+F%22">Morano F</searchLink>; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bergamo+F%22">Bergamo F</searchLink>; Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Maddalena+G%22">Maddalena G</searchLink>; Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.; Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Intini+R%22">Intini R</searchLink>; Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Cremolini+C%22">Cremolini C</searchLink>; Computational Biology Research Centre, Human Technopole, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Caravagna+G%22">Caravagna G</searchLink>; University of Triest, Triest, Italy.<br /><searchLink fieldCode="AU" term="%22Graham+T%22">Graham T</searchLink>; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.; Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Pietrantonio+F%22">Pietrantonio F</searchLink>; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lonardi+S%22">Lonardi S</searchLink>; Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Fassan+M%22">Fassan M</searchLink>; Department of Medicine (DIMED), University of Padua, Padua, Italy.; Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Sottoriva+A%22">Sottoriva A</searchLink>; Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK.; Computational Biology Research Centre, Human Technopole, Milan, Italy.
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              Text: 2025 Feb
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