Genomic ascertainment to quantify prevalence and cancer risk in adults with pathogenic and likely pathogenic germline variants in RASopathy genes.

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Bibliographic Details
Title: Genomic ascertainment to quantify prevalence and cancer risk in adults with pathogenic and likely pathogenic germline variants in RASopathy genes.
Authors: Kim J; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA., Ney G; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA., Frone MN; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA., Haley JS; Department of Genomic Health, Geisinger, Danville, PA, USA., Mirshahi UL; Department of Genomic Health, Geisinger, Danville, PA, USA., Astiazaran-Symonds E; Department of Medicine, College of Medicine-Tucson, University of Arizona, Tucson, AZ USA., Shandrina M; Mindich Child Health and Development Institute and the Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Urban G; Department of Genomic Health, Geisinger, Danville, PA, USA., Rao HS; Department of Genomic Health, Geisinger, Danville, PA, USA., Stahl R; Department of Genomic Health, Geisinger, Danville, PA, USA., Golden A; Department of Genomic Health, Geisinger, Danville, PA, USA., Yohe ME; Laboratory of Cell and Developmental Signaling, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA., Gross AM; Pediatric Oncology Branch, National Cancer Institute, Center for Cancer Research, Bethesda, MD, USA., Ding Y; Department of Genomic Health, Geisinger, Danville, PA, USA., Carey DJ; Department of Genomic Health, Geisinger, Danville, PA, USA., Gelb BD; Mindich Child Health and Development Institute and the Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY USA., Stewart DR; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Oct 11. Date of Electronic Publication: 2024 Oct 11.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
DOI:10.1101/2024.10.09.24314324