ZNFX1 Functions as a Master Regulator of Epigenetically Induced Pathogen Mimicry and Inflammasome Signaling in Cancer.

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Title: ZNFX1 Functions as a Master Regulator of Epigenetically Induced Pathogen Mimicry and Inflammasome Signaling in Cancer.
Authors: Stojanovic L; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, Maryland.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland., Abbotts R; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, Maryland.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland., Tripathi K; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, Maryland.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland., Coon CM; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, Indiana., Rajendran S; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, Indiana., Abbasi Farid E; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, Indiana., Hostetter G; Van Andel Research Institute, Grand Rapids, Michigan., Guarnieri JW; Division of Human Genetics, Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Wallace DC; Division of Human Genetics, Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; Division of Human Genetics, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Liu S; Department of Medical and Molecular Genetics, Indiana University School of Medicine Indianapolis, Indianapolis, Indiana.; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine Indianapolis, Indianapolis, Indiana., Wan J; Department of Medical and Molecular Genetics, Indiana University School of Medicine Indianapolis, Indianapolis, Indiana.; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine Indianapolis, Indianapolis, Indiana., Calendo G; Coriell Institute for Medical Research, Camden, New Jersey., Marker R; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland., Gohari Z; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, Maryland.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland., Inayatullah MMA; University of Southern Denmark, Odense, Denmark., Tiwari VK; University of Southern Denmark, Odense, Denmark., Kader T; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, Massachusetts.; Ludwig Center at Harvard, Boston, Massachusetts., Santagata S; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, Massachusetts.; Ludwig Center at Harvard, Boston, Massachusetts.; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Drapkin R; Department of Obstetrics and Gynecology, Penn Ovarian Cancer Research Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.; Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania., Kommoss S; Institute for Health Informatics, Diakonie-Klinikum Schwäbisch Hall, Schwäbisch Hall, Germany.; Kliniken Essen-Mitte, Gynäkologie und Gynäkologische Onkologie, Essen, Germany., Pfisterer J; Department of Medicine, David Geffen School of Medicine, Los Angeles, California., Konecny GE; University of California Los Angeles, Los Angeles, California., Coopergard R; Institute for Health Informatics, University of Minnesota, Minneapolis, Minnesota., Issa JJ; Coriell Institute for Medical Research, Camden, New Jersey., Winterhoff BJN; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Women's Health (OBGYN), University of Minesota, Minneapolis, Minnesota., Topper MJ; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland., Sandusky GE; Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana., Miller KD; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana.; Division of Hematology/Oncology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana., Baylin SB; Van Andel Research Institute, Grand Rapids, Michigan.; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland., Nephew KP; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, Indiana.; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine Indianapolis, Indianapolis, Indiana.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana., Rassool FV; University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, Maryland.; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland.
Source: Cancer research [Cancer Res] 2025 Apr 03; Vol. 85 (7), pp. 1183-1198.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1538-7445
DOI:10.1158/0008-5472.CAN-24-1286