Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4'-Fluorouridine.
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| Title: | Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4'-Fluorouridine. |
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| Authors: | Yin P; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America., Sobolik EB; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, Washington, United States of America., May NA; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America., Wang S; Institute of Bioengineering, University of Tartu, Tartu, Estonia., Fayed A; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America., Vyshenska D; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, Washington, United States of America., Drobish AM; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America., Parks MG; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America., Lello LS; Institute of Bioengineering, University of Tartu, Tartu, Estonia., Merits A; Institute of Bioengineering, University of Tartu, Tartu, Estonia., Morrison TE; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America., Greninger AL; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, Washington, United States of America., Kielian M; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America. |
| Source: | PLoS pathogens [PLoS Pathog] 2025 Jan 13; Vol. 21 (1), pp. e1012859. Date of Electronic Publication: 2025 Jan 13 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1553-7374 |
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| DOI: | 10.1371/journal.ppat.1012859 |
