View in EDS HTML Full Text PDF Full Text

Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4'-Fluorouridine.

Saved in:
Bibliographic Details
Title: Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4'-Fluorouridine.
Authors: Yin P; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America., Sobolik EB; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, Washington, United States of America., May NA; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America., Wang S; Institute of Bioengineering, University of Tartu, Tartu, Estonia., Fayed A; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America., Vyshenska D; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, Washington, United States of America., Drobish AM; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America., Parks MG; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America., Lello LS; Institute of Bioengineering, University of Tartu, Tartu, Estonia., Merits A; Institute of Bioengineering, University of Tartu, Tartu, Estonia., Morrison TE; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America., Greninger AL; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, Washington, United States of America., Kielian M; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Source: PLoS pathogens [PLoS Pathog] 2025 Jan 13; Vol. 21 (1), pp. e1012859. Date of Electronic Publication: 2025 Jan 13 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39804924
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4'-Fluorouridine.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Yin+P%22">Yin P</searchLink>; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Sobolik+EB%22">Sobolik EB</searchLink>; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22May+NA%22">May NA</searchLink>; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Institute of Bioengineering, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Fayed+A%22">Fayed A</searchLink>; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Vyshenska+D%22">Vyshenska D</searchLink>; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Drobish+AM%22">Drobish AM</searchLink>; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.<br /><searchLink fieldCode="AU" term="%22Parks+MG%22">Parks MG</searchLink>; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.<br /><searchLink fieldCode="AU" term="%22Lello+LS%22">Lello LS</searchLink>; Institute of Bioengineering, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Merits+A%22">Merits A</searchLink>; Institute of Bioengineering, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Morrison+TE%22">Morrison TE</searchLink>; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.<br /><searchLink fieldCode="AU" term="%22Greninger+AL%22">Greninger AL</searchLink>; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Kielian+M%22">Kielian M</searchLink>; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101238921%22">PLoS pathogens</searchLink> [PLoS Pathog] 2025 Jan 13; Vol. 21 (1), pp. e1012859. <i>Date of Electronic Publication: </i>2025 Jan 13 (<i>Print Publication: </i>2025).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101238921 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1553-7374 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215537366%22">15537366 </searchLink><i>NLM ISO Abbreviation: </i>PLoS Pathog <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39804924
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1371/journal.ppat.1012859
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e1012859
    Titles:
      – TitleFull: Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4'-Fluorouridine.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Yin P
      – PersonEntity:
          Name:
            NameFull: Sobolik EB
      – PersonEntity:
          Name:
            NameFull: May NA
      – PersonEntity:
          Name:
            NameFull: Wang S
      – PersonEntity:
          Name:
            NameFull: Fayed A
      – PersonEntity:
          Name:
            NameFull: Vyshenska D
      – PersonEntity:
          Name:
            NameFull: Drobish AM
      – PersonEntity:
          Name:
            NameFull: Parks MG
      – PersonEntity:
          Name:
            NameFull: Lello LS
      – PersonEntity:
          Name:
            NameFull: Merits A
      – PersonEntity:
          Name:
            NameFull: Morrison TE
      – PersonEntity:
          Name:
            NameFull: Greninger AL
      – PersonEntity:
          Name:
            NameFull: Kielian M
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 13
              M: 01
              Text: 2025 Jan 13
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1553-7374
          Numbering:
            – Type: volume
              Value: 21
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: PLoS pathogens
              Type: main
ResultId 1