Acceptability of a dapivirine levonorgestrel vaginal ring in two Phase 1 trials (MTN-030/IPM 041 and MTN-044/IPM 053/CCN019): Implications for multipurpose prevention technology development.

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Title: Acceptability of a dapivirine levonorgestrel vaginal ring in two Phase 1 trials (MTN-030/IPM 041 and MTN-044/IPM 053/CCN019): Implications for multipurpose prevention technology development.
Authors: Friedland BA; Center for Biomedical Research, Population Council, New York, NY, United States of America., Gundacker H; Statistical Center for HIV/AIDS Research and Prevention (SCHARP), Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Achilles SL; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Magee-Womens Research Institute, Pittsburgh, Pennsylvania, United States of America., Chen BA; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Magee-Womens Research Institute, Pittsburgh, Pennsylvania, United States of America., Hoesley C; University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama, United States of America., Richardson BA; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Biostatistics and Global Health, University of Washington, Seattle, Washington, United States of America., Kelly CW; Statistical Center for HIV/AIDS Research and Prevention (SCHARP), Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Piper J; National Institutes of Allergy and Infectious Disease, NIH, Bethesda, Maryland, United States of America., Johnson S; FHI 360, Durham, North Carolina, United States of America., Devlin B; International Partnership for Microbicides, Silver Spring, Maryland, United States of America., Steytler J; International Partnership for Microbicides, Silver Spring, Maryland, United States of America., Kleinbeck K; International Partnership for Microbicides, Silver Spring, Maryland, United States of America., Dangi B; International Partnership for Microbicides, Silver Spring, Maryland, United States of America., Friend C; International Partnership for Microbicides, Silver Spring, Maryland, United States of America., Song M; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Magee-Womens Research Institute, Pittsburgh, Pennsylvania, United States of America., Mensch B; Population Council, New York, NY, United States of America., van der Straten A; RTI International, San Francisco, CA, United States of America., Jacobson C; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Hendrix CW; Division of Clinical Pharmacology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America., Brown J; Contraceptive Development Program, DIPHR, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland, United States of America., Blithe D; Contraceptive Development Program, DIPHR, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland, United States of America., Hiller SL; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Magee-Womens Research Institute, Pittsburgh, Pennsylvania, United States of America.
Corporate Authors: MTN-030/IPM 041 and MTN-044/IPM 053/CCN019 Protocol Teams for the Microbicide Trials Network and the Contraceptive Clinical Trials Network
Source: PloS one [PLoS One] 2025 Jan 14; Vol. 20 (1), pp. e0312957. Date of Electronic Publication: 2025 Jan 14 (Print Publication: 2025).
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0312957