Engineered enzymes for enantioselective nucleophilic aromatic substitutions.

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Bibliographic Details
Title: Engineered enzymes for enantioselective nucleophilic aromatic substitutions.
Authors: Lister TM; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK., Roberts GW; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK., Hossack EJ; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK., Zhao F; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK., Burke AJ; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK., Johannissen LO; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK., Hardy FJ; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK., Millman AAV; Department of Chemistry, The University of Manchester, Manchester, UK., Leys D; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK., Larrosa I; Department of Chemistry, The University of Manchester, Manchester, UK. igor.larrosa@manchester.ac.uk., Green AP; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK. anthony.green@manchester.ac.uk.; Department of Chemistry, The University of Manchester, Manchester, UK. anthony.green@manchester.ac.uk.
Source: Nature [Nature] 2025 Mar; Vol. 639 (8054), pp. 375-381. Date of Electronic Publication: 2025 Jan 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4687
DOI:10.1038/s41586-025-08611-0