Engineered enzymes for enantioselective nucleophilic aromatic substitutions.

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Title: Engineered enzymes for enantioselective nucleophilic aromatic substitutions.
Authors: Lister TM; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK., Roberts GW; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK., Hossack EJ; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK., Zhao F; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK., Burke AJ; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK., Johannissen LO; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK., Hardy FJ; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK., Millman AAV; Department of Chemistry, The University of Manchester, Manchester, UK., Leys D; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK., Larrosa I; Department of Chemistry, The University of Manchester, Manchester, UK. igor.larrosa@manchester.ac.uk., Green AP; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK. anthony.green@manchester.ac.uk.; Department of Chemistry, The University of Manchester, Manchester, UK. anthony.green@manchester.ac.uk.
Source: Nature [Nature] 2025 Mar; Vol. 639 (8054), pp. 375-381. Date of Electronic Publication: 2025 Jan 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Lister+TM%22">Lister TM</searchLink>; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Roberts+GW%22">Roberts GW</searchLink>; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Hossack+EJ%22">Hossack EJ</searchLink>; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Zhao+F%22">Zhao F</searchLink>; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Burke+AJ%22">Burke AJ</searchLink>; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Johannissen+LO%22">Johannissen LO</searchLink>; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Hardy+FJ%22">Hardy FJ</searchLink>; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Millman+AAV%22">Millman AAV</searchLink>; Department of Chemistry, The University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Leys+D%22">Leys D</searchLink>; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.; Department of Chemistry, The University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Larrosa+I%22">Larrosa I</searchLink>; Department of Chemistry, The University of Manchester, Manchester, UK. igor.larrosa@manchester.ac.uk.<br /><searchLink fieldCode="AU" term="%22Green+AP%22">Green AP</searchLink>; Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK. anthony.green@manchester.ac.uk.; Department of Chemistry, The University of Manchester, Manchester, UK. anthony.green@manchester.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2025 Mar; Vol. 639 (8054), pp. 375-381. <i>Date of Electronic Publication: </i>2025 Jan 15.
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        Value: 10.1038/s41586-025-08611-0
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              Text: 2025 Mar
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