Inactivation of glutathione S-transferase alpha 4 blocks Enterococcus faecalis-induced bystander effect by promoting macrophage ferroptosis.

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Title: Inactivation of glutathione S-transferase alpha 4 blocks Enterococcus faecalis-induced bystander effect by promoting macrophage ferroptosis.
Authors: Ju Y; Nantong Institute of Genetics and Reproductive Medicine, Affiliated Maternity and Child Healthcare Hospital of Nantong University, Nantong, Jiangsu, China.; Nantong Key Laboratory of Genetics and Reproductive Medicine, Nantong, Jiangsu, China., Ma C; Nantong Institute of Genetics and Reproductive Medicine, Affiliated Maternity and Child Healthcare Hospital of Nantong University, Nantong, Jiangsu, China.; Nantong Key Laboratory of Genetics and Reproductive Medicine, Nantong, Jiangsu, China., Huang L; Department of Gastroenterology, Affiliated Maternity and Child Healthcare Hospital of Nantong University, Nantong, Jiangsu, China., Tao Y; Department of Pathology, Affiliated Maternity and Child Healthcare Hospital of Nantong University, Nantong, Jiangsu, China., Li T; Nantong Institute of Genetics and Reproductive Medicine, Affiliated Maternity and Child Healthcare Hospital of Nantong University, Nantong, Jiangsu, China.; Nantong Key Laboratory of Genetics and Reproductive Medicine, Nantong, Jiangsu, China., Li H; Department of Clinical Laboratory, Affiliated Maternity and Child Healthcare Hospital of Nantong University, Nantong, Jiangsu, China., Huycke MM; Stephenson Cancer Center, Department of Radiation Oncology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Yang Y; Department of Nephrology, Rheumatology, and Immunology, Nantong Children's Hospital, Nantong, Jiangsu, China.; Department of Pediatrics, Nantong Maternity and Child Healthcare Hospital, Nantong, Jiangsu, China., Wang X; Nantong Institute of Genetics and Reproductive Medicine, Affiliated Maternity and Child Healthcare Hospital of Nantong University, Nantong, Jiangsu, China.; Nantong Key Laboratory of Genetics and Reproductive Medicine, Nantong, Jiangsu, China.; Stephenson Cancer Center, Department of Radiation Oncology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Source: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2451090. Date of Electronic Publication: 2025 Jan 16.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1949-0984
DOI:10.1080/19490976.2025.2451090