Human ACE2 transgenic pigs are susceptible to SARS-CoV-2 and develop COVID-19-like disease.

Saved in:
Bibliographic Details
Title: Human ACE2 transgenic pigs are susceptible to SARS-CoV-2 and develop COVID-19-like disease.
Authors: Chau LF; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK., Lillico S; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK., Opriessnig T; Moredun Research Institute, Edinburgh, UK., Blake R; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK., Tardy L; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK., Lee CH; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK., Maxwell S; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK., Warren C; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK., Thornton E; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK., Mclaughlin CL; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK., McLachlan G; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK., Tait-Burkard C; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK., Fletcher S; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK., Anderson S; Moredun Research Institute, Edinburgh, UK., Brown S; Moredun Research Institute, Edinburgh, UK., Gibbard L; Moredun Research Institute, Edinburgh, UK., Tzelos T; Moredun Research Institute, Edinburgh, UK., MacMillan-Christensen D; Moredun Research Institute, Edinburgh, UK., Baillie JK; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.; Baillie Gifford Pandemic Science Hub, University of Edinburgh, Edinburgh, UK., Dorward DA; Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, UK.; Department of Pathology, Royal Infirmary, Edinburgh, UK., Griffiths DJ; Moredun Research Institute, Edinburgh, UK. David.Griffiths@moredun.ac.uk., Grey F; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK. fgrey@exseed.ed.ac.uk.
Source: Nature communications [Nat Commun] 2025 Jan 17; Vol. 16 (1), pp. 766. Date of Electronic Publication: 2025 Jan 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39824810
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Human ACE2 transgenic pigs are susceptible to SARS-CoV-2 and develop COVID-19-like disease.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Chau+LF%22">Chau LF</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Lillico+S%22">Lillico S</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Opriessnig+T%22">Opriessnig T</searchLink>; Moredun Research Institute, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Blake+R%22">Blake R</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Tardy+L%22">Tardy L</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Lee+CH%22">Lee CH</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Maxwell+S%22">Maxwell S</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Warren+C%22">Warren C</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Thornton+E%22">Thornton E</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Mclaughlin+CL%22">Mclaughlin CL</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22McLachlan+G%22">McLachlan G</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Tait-Burkard+C%22">Tait-Burkard C</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Fletcher+S%22">Fletcher S</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Anderson+S%22">Anderson S</searchLink>; Moredun Research Institute, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Brown+S%22">Brown S</searchLink>; Moredun Research Institute, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Gibbard+L%22">Gibbard L</searchLink>; Moredun Research Institute, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Tzelos+T%22">Tzelos T</searchLink>; Moredun Research Institute, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22MacMillan-Christensen+D%22">MacMillan-Christensen D</searchLink>; Moredun Research Institute, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Baillie+JK%22">Baillie JK</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.; Baillie Gifford Pandemic Science Hub, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Dorward+DA%22">Dorward DA</searchLink>; Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, UK.; Department of Pathology, Royal Infirmary, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Griffiths+DJ%22">Griffiths DJ</searchLink>; Moredun Research Institute, Edinburgh, UK. David.Griffiths@moredun.ac.uk.<br /><searchLink fieldCode="AU" term="%22Grey+F%22">Grey F</searchLink>; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK. fgrey@exseed.ed.ac.uk.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Jan 17; Vol. 16 (1), pp. 766. <i>Date of Electronic Publication: </i>2025 Jan 17.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39824810
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-024-54615-1
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 766
    Titles:
      – TitleFull: Human ACE2 transgenic pigs are susceptible to SARS-CoV-2 and develop COVID-19-like disease.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Chau LF
      – PersonEntity:
          Name:
            NameFull: Lillico S
      – PersonEntity:
          Name:
            NameFull: Opriessnig T
      – PersonEntity:
          Name:
            NameFull: Blake R
      – PersonEntity:
          Name:
            NameFull: Tardy L
      – PersonEntity:
          Name:
            NameFull: Lee CH
      – PersonEntity:
          Name:
            NameFull: Maxwell S
      – PersonEntity:
          Name:
            NameFull: Warren C
      – PersonEntity:
          Name:
            NameFull: Thornton E
      – PersonEntity:
          Name:
            NameFull: Mclaughlin CL
      – PersonEntity:
          Name:
            NameFull: McLachlan G
      – PersonEntity:
          Name:
            NameFull: Tait-Burkard C
      – PersonEntity:
          Name:
            NameFull: Fletcher S
      – PersonEntity:
          Name:
            NameFull: Anderson S
      – PersonEntity:
          Name:
            NameFull: Brown S
      – PersonEntity:
          Name:
            NameFull: Gibbard L
      – PersonEntity:
          Name:
            NameFull: Tzelos T
      – PersonEntity:
          Name:
            NameFull: MacMillan-Christensen D
      – PersonEntity:
          Name:
            NameFull: Baillie JK
      – PersonEntity:
          Name:
            NameFull: Dorward DA
      – PersonEntity:
          Name:
            NameFull: Griffiths DJ
      – PersonEntity:
          Name:
            NameFull: Grey F
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 17
              M: 01
              Text: 2025 Jan 17
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1