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Targeting unique ligand binding domain structural features downregulates DKK1 in Y537S ESR1 mutant breast cancer cells.

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Bibliographic Details
Title: Targeting unique ligand binding domain structural features downregulates DKK1 in Y537S ESR1 mutant breast cancer cells.
Authors: Young KS; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 50153, USA., Hancock GR; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 50153, USA., Fink EC; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 50153, USA., Zigrossi A; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 50153, USA., Flowers B; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 50153, USA., Cooper DA; Department of Chemistry, Illinois Institute of Technology, Chicago, IL, 60616, USA., Nguyen VT; Department of Chemistry, Illinois Institute of Technology, Chicago, IL, 60616, USA., Martinez MC; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 50153, USA., Mon KS; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 50153, USA., Bosland M; Department of Pathology, University of Illinois Chicago, Chicago, IL, 60607, USA., Zak DR; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 50153, USA., Runde AP; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 50153, USA., Sharifi MN; Department of Medicine, University of Wisconsin, Madison, WI, 53705, USA., Kastrati I; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 50153, USA., Minh DDL; Department of Chemistry, Illinois Institute of Technology, Chicago, IL, 60616, USA., Kregel S; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 50153, USA., Fanning SW; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 50153, USA. sfanning@luc.edu.
Source: Breast cancer research : BCR [Breast Cancer Res] 2025 Jan 17; Vol. 27 (1), pp. 10. Date of Electronic Publication: 2025 Jan 17.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1465-542X
DOI:10.1186/s13058-024-01945-z