Preliminary effects of oral ANS-6637, an ALDH2 inhibitor, on cue-induced craving, safety and alcohol consumption among adults with alcohol use disorder: a proof-of-concept, randomized, human laboratory trial.
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| Title: | Preliminary effects of oral ANS-6637, an ALDH2 inhibitor, on cue-induced craving, safety and alcohol consumption among adults with alcohol use disorder: a proof-of-concept, randomized, human laboratory trial. |
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| Authors: | O'Malley SS; Department of Psychiatry, Yale School of Medicine, 34 Park Street, New Haven, CT 06519, United States., Miranda R Jr; Department of Psychiatry and Human Behavior, Brown University, 121 S. Main Street, Providence, RI 02912, United States., Book SW; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, United States., Chun TH; Departments of Emergency Medicine and Pediatrics, Alpert Medical School of Brown University, Rhode Island Hospital, Claverick 2, 593 Eddy Street, Providence, RI 02903, United States., Liss T; Department of Psychiatry, Yale School of Medicine, 34 Park Street, New Haven, CT 06519, United States., Malcolm RJ; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, United States., Muvvala SB; Department of Psychiatry, Yale School of Medicine, 34 Park Street, New Haven, CT 06519, United States., Padovano HT; Department of Psychiatry and Human Behavior, Brown University, 121 S. Main Street, Providence, RI 02912, United States., Schacht JP; Department of Psychiatry, University of Colorado School of Medicine, 1890 N. Revere Court, Mail Stop F570, Aurora, CO 80045, United States., Blackburn B; Amygdala Neurosciences, Inc., 5214F Diamond Heights Blvd #151, San Francisco, CA 94131, United States., Diamond I; Amygdala Neurosciences, Inc., 5214F Diamond Heights Blvd #151, San Francisco, CA 94131, United States., Ransom J; Fast-Track Drugs & Biologics, LLC, 20010 Fisher Avenue, Suite G, Poolesville, MD 20837, United States., Ryan ML; Division of Treatment and Recovery, National Institute on Alcohol Abuse and Alcoholism, 6700 B Rockledge Drive, Bethesda, MD 20892, United States., Falk DE; Division of Treatment and Recovery, National Institute on Alcohol Abuse and Alcoholism, 6700 B Rockledge Drive, Bethesda, MD 20892, United States., Litten RZ; Division of Treatment and Recovery, National Institute on Alcohol Abuse and Alcoholism, 6700 B Rockledge Drive, Bethesda, MD 20892, United States. |
| Source: | Alcohol and alcoholism (Oxford, Oxfordshire) [Alcohol Alcohol] 2025 Jan 19; Vol. 60 (2). |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 8310684 Publication Model: Print Cited Medium: Internet ISSN: 1464-3502 (Electronic) Linking ISSN: 07350414 NLM ISO Abbreviation: Alcohol Alcohol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1464-3502 |
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| DOI: | 10.1093/alcalc/agaf001 |
