Discovery of 2-Pyrazolines That Inhibit the Phosphorylation of STAT3 as Nanomolar Cytotoxic Agents.

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Title: Discovery of 2-Pyrazolines That Inhibit the Phosphorylation of STAT3 as Nanomolar Cytotoxic Agents.
Authors: Siddappa TP; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India., Ravish A; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India., Xi Z; Shenzhen Bay Laboratory, Shenzhen 518055, China., Mohan A; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India., Girimanchanaika SS; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India., Krishnamurthy NP; NMR Research Centre, Indian Institute of Science, Bangalore, Karnataka 560012, India., Basappa S; Department of Chemistry, BITS-Pilani Hyderabad Campus, Jawahar Nagar, Medchal 500078, India., Gaonkar SL; Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, Karnataka 576104, India., Lobie PE; Shenzhen Bay Laboratory, Shenzhen 518055, China.; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China., Pandey V; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China., Basappa B; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India.
Source: ACS omega [ACS Omega] 2025 Jan 02; Vol. 10 (1), pp. 114-126. Date of Electronic Publication: 2025 Jan 02 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE
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  Data: Discovery of 2-Pyrazolines That Inhibit the Phosphorylation of STAT3 as Nanomolar Cytotoxic Agents.
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  Data: <searchLink fieldCode="AU" term="%22Siddappa+TP%22">Siddappa TP</searchLink>; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India.<br /><searchLink fieldCode="AU" term="%22Ravish+A%22">Ravish A</searchLink>; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India.<br /><searchLink fieldCode="AU" term="%22Xi+Z%22">Xi Z</searchLink>; Shenzhen Bay Laboratory, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Mohan+A%22">Mohan A</searchLink>; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India.<br /><searchLink fieldCode="AU" term="%22Girimanchanaika+SS%22">Girimanchanaika SS</searchLink>; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India.<br /><searchLink fieldCode="AU" term="%22Krishnamurthy+NP%22">Krishnamurthy NP</searchLink>; NMR Research Centre, Indian Institute of Science, Bangalore, Karnataka 560012, India.<br /><searchLink fieldCode="AU" term="%22Basappa+S%22">Basappa S</searchLink>; Department of Chemistry, BITS-Pilani Hyderabad Campus, Jawahar Nagar, Medchal 500078, India.<br /><searchLink fieldCode="AU" term="%22Gaonkar+SL%22">Gaonkar SL</searchLink>; Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, Karnataka 576104, India.<br /><searchLink fieldCode="AU" term="%22Lobie+PE%22">Lobie PE</searchLink>; Shenzhen Bay Laboratory, Shenzhen 518055, China.; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Pandey+V%22">Pandey V</searchLink>; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Basappa+B%22">Basappa B</searchLink>; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, Karnataka 570006, India.
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  Data: <searchLink fieldCode="JN" term="%22101691658%22">ACS omega</searchLink> [ACS Omega] 2025 Jan 02; Vol. 10 (1), pp. 114-126. <i>Date of Electronic Publication: </i>2025 Jan 02 (<i>Print Publication: </i>2025).
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              Text: 2025 Jan 02
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