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Rapid and scalable personalized ASO screening in patient-derived organoids.

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Bibliographic Details
Title: Rapid and scalable personalized ASO screening in patient-derived organoids.
Authors: Means JC; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA., Martinez-Bengochea AL; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA., Louiselle DA; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA., Nemechek JM; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA., Perry JM; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.; Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS, USA., Farrow EG; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA., Pastinen T; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.; Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS, USA., Younger ST; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA. styounger@cmh.edu.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA. styounger@cmh.edu.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA. styounger@cmh.edu.; Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS, USA. styounger@cmh.edu.
Source: Nature [Nature] 2025 Feb; Vol. 638 (8049), pp. 237-243. Date of Electronic Publication: 2025 Jan 22.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4687
DOI:10.1038/s41586-024-08462-1