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Rapid and scalable personalized ASO screening in patient-derived organoids.

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Title: Rapid and scalable personalized ASO screening in patient-derived organoids.
Authors: Means JC; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA., Martinez-Bengochea AL; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA., Louiselle DA; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA., Nemechek JM; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA., Perry JM; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.; Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS, USA., Farrow EG; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA., Pastinen T; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.; Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS, USA., Younger ST; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA. styounger@cmh.edu.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA. styounger@cmh.edu.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA. styounger@cmh.edu.; Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS, USA. styounger@cmh.edu.
Source: Nature [Nature] 2025 Feb; Vol. 638 (8049), pp. 237-243. Date of Electronic Publication: 2025 Jan 22.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: Rapid and scalable personalized ASO screening in patient-derived organoids.
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  Data: <searchLink fieldCode="AU" term="%22Means+JC%22">Means JC</searchLink>; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Martinez-Bengochea+AL%22">Martinez-Bengochea AL</searchLink>; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Louiselle+DA%22">Louiselle DA</searchLink>; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Nemechek+JM%22">Nemechek JM</searchLink>; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Perry+JM%22">Perry JM</searchLink>; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.; Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS, USA.<br /><searchLink fieldCode="AU" term="%22Farrow+EG%22">Farrow EG</searchLink>; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Pastinen+T%22">Pastinen T</searchLink>; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.; Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS, USA.<br /><searchLink fieldCode="AU" term="%22Younger+ST%22">Younger ST</searchLink>; Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA. styounger@cmh.edu.; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, MO, USA. styounger@cmh.edu.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA. styounger@cmh.edu.; Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS, USA. styounger@cmh.edu.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2025 Feb; Vol. 638 (8049), pp. 237-243. <i>Date of Electronic Publication: </i>2025 Jan 22.
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              Text: 2025 Feb
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