The conformational landscape of human transthyretin revealed by cryo-EM.

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Title: The conformational landscape of human transthyretin revealed by cryo-EM.
Authors: Basanta B; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA, USA.; Arzeda, Seattle, WA, USA., Nugroho K; Department of Chemistry, Scripps Research, La Jolla, CA, USA., Yan NL; Department of Chemistry, Scripps Research, La Jolla, CA, USA., Kline GM; Department of Chemistry, Scripps Research, La Jolla, CA, USA., Powers ET; Department of Chemistry, Scripps Research, La Jolla, CA, USA., Tsai FJ; Department of Chemistry, Scripps Research, La Jolla, CA, USA., Wu M; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA, USA.; Neomorph, San Diego, CA, USA., Hansel-Harris A; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA, USA., Chen JS; Automated Synthesis Facility, Scripps Research, La Jolla, CA, USA., Forli S; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA, USA., Kelly JW; Department of Chemistry, Scripps Research, La Jolla, CA, USA., Lander GC; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA, USA. glander@scripps.edu.
Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2025 May; Vol. 32 (5), pp. 876-883. Date of Electronic Publication: 2025 Jan 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1545-9985
DOI:10.1038/s41594-024-01472-7