APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology.
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| Title: | APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology. |
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| Authors: | Tran KM; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Kwang NE; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Butler CA; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Gomez-Arboledas A; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA., Kawauchi S; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA.; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Mar C; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Chao D; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Barahona RA; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Da Cunha C; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA., Tsourmas KI; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Shi Z; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Wang S; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Collins S; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Walker A; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Shi KX; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Alcantara JA; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Neumann J; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA., Duong DM; ARCProteomics, Atlanta, GA, 30322, USA., Seyfried NT; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA, 30322, USA., Tenner AJ; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA.; Department of Molecular Biology & Biochemistry, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697, USA.; Department of Pathology and Laboratory Medicine, University of California, Irvine, CA, 92697, USA., LaFerla FM; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA., Hohsfield LA; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA., Swarup V; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA.; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA.; Center for Complex Biological Systems, University of California, Irvine, CA, 92697, USA., MacGregor GR; Transgenic Mouse Facility, ULAR, Office of Research, University of California, Irvine, CA, 92697-2300, USA. gmacg@uci.edu.; Department of Developmental and Cell Biology, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697, USA. gmacg@uci.edu., Green KN; Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, 92697-4545, USA. kngreen@uci.edu.; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697, USA. kngreen@uci.edu. |
| Source: | Molecular neurodegeneration [Mol Neurodegener] 2025 Jan 22; Vol. 20 (1), pp. 9. Date of Electronic Publication: 2025 Jan 22. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1750-1326 |
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| DOI: | 10.1186/s13024-024-00793-x |
